Wuerthner, Jens U.

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

Townsend, E. C., Murakami, M. A., Christodoulou, A., Christie, A. L., Köster, J., DeSouza, T. A., Morgan, E. A., Kallgren, S. P., Liu, H., Wu, S.-C., et al. (2016) · Cancer Cell

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The public repository of xenografts enables discovery and randomized phase II-like trials in mice

Townsend, E. C., Murakami, M. A., Christodoulou, A., Christie, A. L., Köster, J., DeSouza, T. A., Morgan, E. A., Kallgren, S. P., Liu, H., Wu, S.-C., et al. (2016) · Cancer Cell

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

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Inhibition of Wild-Type p53-Expressing AML by the Novel Small Molecule HDM2 Inhibitor CGM097

Weisberg, E., Halilovic, E., Cooke, V. G., Nonami, A., Ren, T., Sanda, T., Simkin, I., Yuan, J., Antonakos, B., Barys, L., et al. (2015) · Molecular Cancer Therapeutics

Cancer-related Molecular PathwaysAcute Myeloid Leukemia Research

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Combined ALK and MDM2 inhibition increases antitumor activity and overcomes resistance in human ALK mutant neuroblastoma cell lines and xenograft models

Wang, H. Q., Halilovic, E., Li, X., Liang, J., Cao, Y., Rakiec, D. P., Ruddy, D. A., Jeay, S., Wuerthner, J. U., Timple, N., et al. (2017) · eLife

Neuroblastoma Research and TreatmentsLung Cancer Treatments and Mutations

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The MDM2 Inhibitor NVP-CGM097 Is Highly Active in a Randomized Preclinical Trial of B-Cell Acute Lymphoblastic Leukemia Patient Derived Xenografts

Townsend, E. C., DeSouza, T., Murakami, M. A., Montero, J., Stevenson, K., Christie, A. L., Christodolou, A. N., Vojinovic, U., Kopp, N., Barzaghi-Rinaudo, P., et al. (2015) · Blood

Acute Lymphoblastic Leukemia researchCancer-related Molecular Pathways

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