Oppermann, Udo

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Kruidenier, L., Chung, C.-W., Cheng, Z., Liddle, J., Che, K., Joberty, G., Bantscheff, M., Bountra, C., Bridges, A., Diallo, H., et al. (2012) · Nature

Epigenetics and DNA MethylationCancer-related gene regulation

Cited by 950

Medium- and short-chain dehydrogenase/reductase gene and protein families: The SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes

Kavanagh, K. L., Jörnvall, H., Persson, B., & Oppermann, U. (2008) · Cellular and Molecular Life Sciences

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 908

Critical Residues for Structure and Catalysis in Short-chain Dehydrogenases/Reductases

Filling, C., Berndt, K. D., Benach, J., Knapp, S., Prozorovski, T., Nordling, E., Ladenstein, R., Jörnvall, H., & Oppermann, U. (2002) · Journal of Biological Chemistry

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 583

The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway

Carbonneau, M., M. Gagné, L., Lalonde, M.-E., Germain, M.-A., Motorina, A., Guiot, M.-C., Secco, B., Vincent, E. E., Tumber, A., Hulea, L., et al. (2016) · Nature Communications

Cancer, Hypoxia, and MetabolismPI3K/AKT/mTOR signaling in cancer

Cited by 180

Reversible Sequestration of Active Site Cysteines in a 2Fe-2S-bridged Dimer Provides a Mechanism for Glutaredoxin 2 Regulation in Human Mitochondria

Johansson, C., Kavanagh, K. L., Gileadi, O., & Oppermann, U. (2007) · Journal of Biological Chemistry

Redox biology and oxidative stressSulfur Compounds in Biology

Cited by 147

Ribosomal oxygenases are structurally conserved from prokaryotes to humans

Chowdhury, R., Sekirnik, R., Brissett, N. C., Krojer, T., Ho, C.-H., Ng, S. S., Clifton, I. J., Ge, W., Kershaw, N. J., Fox, G. C., et al. (2014) · Nature

Metal-Catalyzed Oxygenation MechanismsEnzyme Structure and Function

Cited by 105

The 11β‐Hydroxysteroid Dehydrogenase System, A Determinant of Glucocorticoid and Mineralocorticoid Action: Function, Gene Organization and Protein Structures of 11β‐Hydroxysteroid Dehydrogenase Isoforms

Oppermann, U. C. T., Persson, B., & Jörnvall, H. (1997) · European Journal of Biochemistry

Hormonal Regulation and HypertensionAdrenal Hormones and Disorders

Cited by 66