Gottesman, Michael M.

Multidrug resistance in cancer: role of ATP–dependent transporters

Gottesman, M. M., Fojo, T., & Bates, S. E. (2002) · Nature Reviews Cancer

Drug Transport and Resistance MechanismsAntibiotic Resistance in Bacteria

Cited by 5,536

Targeting multidrug resistance in cancer

Szakács, G., Paterson, J. K., Ludwig, J. A., Booth-Genthe, C., & Gottesman, M. M. (2006) · Nature Reviews Drug Discovery

Drug Transport and Resistance MechanismsAntibiotic Resistance in Bacteria

Cited by 3,609

Mechanisms of Cancer Drug Resistance

Gottesman, M. M. (2002) · Annual Review of Medicine

Drug Transport and Resistance MechanismsCancer Cells and Metastasis

Cited by 2,643

A "Silent" Polymorphism in the MDR 1 Gene Changes Substrate Specificity

Kimchi-Sarfaty, C., Oh, J. M., Kim, I.-W., Sauna, Z. E., Calcagno, A. M., Ambudkar, S. V., & Gottesman, M. M. (2007) · Science

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 2,416

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

Chen, C.-J., Chin, J. E., Ueda, K., Clark, D. P., Pastan, I., Gottesman, M. M., & Roninson, I. B. (1986) · Cell

Drug Transport and Resistance MechanismsAntibiotic Resistance in Bacteria

Cited by 1,898

Revisiting the role of ABC transporters in multidrug-resistant cancer

Robey, R. W., Pluchino, K. M., Hall, M. D., Fojo, A. T., Bates, S. E., & Gottesman, M. M. (2018) · Nature Reviews Cancer

Drug Transport and Resistance MechanismsAntibiotic Resistance in Bacteria

Cited by 1,866

Cisplatin Resistance: A Cellular Self-Defense Mechanism Resulting from Multiple Epigenetic and Genetic Changes

Shen, D.-W., Pouliot, L. M., Hall, M. D., & Gottesman, M. M. (2012) · Pharmacological Reviews

Metal complexes synthesis and propertiesDrug Transport and Resistance Mechanisms

Cited by 955

The molecular basis of multidrug resistance in cancer: The early years of P‐glycoprotein research

Gottesman, M. M., & Ling, V. (2006) · FEBS Letters

Drug Transport and Resistance MechanismsAntibiotic Resistance in Bacteria

Cited by 558

Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

Gillet, J.-P., Calcagno, A. M., Varma, S., Marino, M., Green, L. J., Vora, M. I., Patel, C., Orina, J. N., Eliseeva, T. A., Singal, V., et al. (2011) · Proceedings of the National Academy of Sciences

Drug Transport and Resistance MechanismsCancer Cells and Metastasis

Cited by 477

Say no to DMSO: dimethylsulfoxide inactivates cisplatin, carboplatin, and other platinum complexes

Hall, M. D., Telma, K. A., Chang, K.-E., Lee, T. D., Madigan, J. P., Lloyd, J. R., Goldlust, I. S., Hoeschele, J. D., & Gottesman, M. M. (2014) · Cancer Research

Metal complexes synthesis and propertiesCancer therapeutics and mechanisms

Cited by 377

The Inhibitor Ko143 Is Not Specific for ABCG2

Weidner, L. D., Zoghbi, S. S., Lu, S., Shukla, S., Ambudkar, S. V., Pike, V. W., Mulder, J., Gottesman, M. M., Innis, R. B., & Hall, M. D. (2015) · The Journal of Pharmacology and Experimental Therapeutics

Drug Transport and Resistance MechanismsBarrier Structure and Function Studies

Cited by 141

The thiol methyltransferase activity of TMT1A (METTL7A) is conserved across species

González Dalmasy, J. M., Fitzsimmons, C. M., Frye, W. J. E., Perciaccante, A. J., Jewell, C. P., Jenkins, L. M., Batista, P. J., Robey, R. W., & Gottesman, M. M. (2023) · Chemico-Biological Interactions

Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation

Cited by 3

The thiol methyltransferase activity of TMT1A (METTL7A) is conserved across species

González Dalmasy, J. M., Fitzsimmons, C. M., Frye, W. J. E., Perciaccante, A. J., Jewell, C. P., Jenkins, L. M., Batista, P. J., Robey, R. W., & Gottesman, M. M. (2024) · Chemico-Biological Interactions

Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation

Cited by 3