Metzen, Eric

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

Epstein, A. C. R., Gleadle, J. M., McNeill, L. A., Hewitson, K. S., O'Rourke, J., Mole, D. R., Mukherji, M., Metzen, E., Wilson, M. I., Dhanda, A., et al. (2001) · Cell

Cancer, Hypoxia, and MetabolismMetal-Catalyzed Oxygenation Mechanisms

Cited by 3,333

Intracellular localisation of human HIF-1α hydroxylases:implications for oxygen sensing

Metzen, E., Berchner-Pfannschmidt, U., Stengel, P., Marxsen, J. H., Stolze, I., Klinger, M., Huang, W. Q., Wotzlaw, C., Hellwig-Bürgel, T., Jelkmann, W., et al. (2003) · Journal of Cell Science

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 432

Nitric Oxide Impairs Normoxic Degradation of HIF-1α by Inhibition of Prolyl Hydroxylases

Metzen, E., Zhou, J., Jelkmann, W., Fandrey, J., & Brüne, B. (2003) · Molecular Biology of the Cell

Cancer, Hypoxia, and MetabolismNitric Oxide and Endothelin Effects

Cited by 414

Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-α-prolyl-4-hydroxylases

MARXSEN, J. H., STENGEL, P., DOEGE, K., HEIKKINEN, P., JOKILEHTO, T., WAGNER, T., JELKMANN, W., JAAKKOLA, P., & METZEN, E. (2004) · Biochemical Journal

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 386

Pericellular PO2 and O2 Consumption in Monolayer Cell Cultures

Metzen, E., Wolff, M., Fandrey, J., & Jelkmann, W. (1995) · Respiration Physiology

Cancer, Hypoxia, and MetabolismBiomedical and Chemical Research

Cited by 153

Inhibition of mitochondrial respiration elevates oxygen concentration but leaves regulation of hypoxia-inducible factor (HIF) intact

Doege, K., Heine, S., Jensen, I., Jelkmann, W., & Metzen, E. (2005) · Blood

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 128