Sørensen, Claus Storgaard

The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

Sørensen, C. S., Hansen, L. T., Dziegielewski, J., Syljuåsen, R. G., Lundin, C., Bartek, J., & Helleday, T. (2005) · Nature Cell Biology

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 666

Hereditary breast and ovarian cancer: new genes in confined pathways

Nielsen, F. C., van Overeem Hansen, T., & Sørensen, C. S. (2016) · Nature Reviews Cancer

BRCA gene mutations in cancerGenetic factors in colorectal cancer

Cited by 367

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

Galanos, P., Vougas, K., Walter, D., Polyzos, A., Maya-Mendoza, A., Haagensen, E. J., Kokkalis, A., Roumelioti, F.-M., Gagos, S., Tzetis, M., et al. (2016) · Nature Cell Biology

Cancer-related Molecular PathwaysTelomeres, Telomerase, and Senescence

Cited by 308

Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing radiation

Syljuåsen, R. G., Sørensen, C. S., Nylandsted, J., Lukas, C., Lukas, J., & Bartek, J. (2004) · Cancer Research

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 99

Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability

Galanos, P., Pappas, G., Polyzos, A., Kotsinas, A., Svolaki, I., Giakoumakis, N. N., Glytsou, C., Pateras, I. S., Swain, U., Souliotis, V. L., et al. (2018) · Genome Biology

DNA Repair MechanismsCancer Genomics and Diagnostics

Cited by 67

WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity

Elbæk, C. R., Petrosius, V., Benada, J., Erichsen, L., Damgaard, R. B., & Sørensen, C. S. (2022) · Cell Reports

DNA Repair MechanismsCancer-related Molecular Pathways

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