Alberch, Jordi

Developmental alterations in Huntington’s disease neural cells and pharmacological rescue in cells and mice

The HD iPSC Consortium, Lim, R. G., Salazar, L. L., Wilton, D. K., King, A. R., Stocksdale, J. T., Sharifabad, D., Lau, A. L., Stevens, B., Reidling, J. C., et al. (2017) · Nature Neuroscience

Genetic Neurodegenerative DiseasesPluripotent Stem Cells Research

Cited by 221

Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTRup-regulation and astrocyte-mediated inflammation

Miguez, A., García-Díaz Barriga, G., Brito, V., Straccia, M., Giralt, A., Ginés, S., Canals, J. M., & Alberch, J. (2015) · Human Molecular Genetics

Genetic Neurodegenerative DiseasesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 126

Neurotrophin receptor p75NTR mediates Huntington’s disease–associated synaptic and memory dysfunction

Brito, V., Giralt, A., Enriquez-Barreto, L., Puigdellívol, M., Suelves, N., Zamora-Moratalla, A., Ballesteros, J. J., Martín, E. D., Dominguez-Iturza, N., Morales, M., et al. (2014) · Journal of Clinical Investigation

Genetic Neurodegenerative DiseasesNeuroscience and Neuropharmacology Research

Cited by 114

Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington’s disease model

Giralt, A., Brito, V., Chevy, Q., Simonnet, C., Otsu, Y., Cifuentes-Díaz, C., de Pins, B., Coura, R., Alberch, J., Ginés, S., et al. (2017) · Nature Communications

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 102

Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism

del Toro, D., Canals, J. M., Ginés, S., Kojima, M., Egea, G., & Alberch, J. (2006) · The Journal of Neuroscience

Genetic Neurodegenerative DiseasesCellular transport and secretion

Cited by 95