Mele, Aldo

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

Darnell, J. C., Van Driesche, S. J., Zhang, C., Hung, K. Y. S., Mele, A., Fraser, C. E., Stone, E. F., Chen, C., Fak, J. J., Chi, S. W., et al. (2011) · Cell

Genetics and Neurodevelopmental DisordersRNA and protein synthesis mechanisms

Cited by 2,072

Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps

Chi, S. W., Zang, J. B., Mele, A., & Darnell, R. B. (2009) · Nature

MicroRNA in disease regulationRNA Research and Splicing

Cited by 1,791

HITS-CLIP yields genome-wide insights into brain alternative RNA processing

Licatalosi, D. D., Mele, A., Fak, J. J., Ule, J., Kayikci, M., Chi, S. W., Clark, T. A., Schweitzer, A. C., Blume, J. E., Wang, X., et al. (2008) · Nature

RNA Research and SplicingRNA regulation and disease

Cited by 1,352

CLIP Identifies Nova-Regulated RNA Networks in the Brain

Ule, J., Jensen, K. B., Ruggiu, M., Mele, A., Ule, A., & Darnell, R. B. (2003) · Science

RNA Research and SplicingRNA regulation and disease

Cited by 1,120

HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism

Weyn-Vanhentenryck, S. M., Mele, A., Yan, Q., Sun, S., Farny, N., Zhang, Z., Xue, C., Herre, M., Silver, P. A., Zhang, M. Q., et al. (2014) · Cell Reports

RNA Research and SplicingGenetics and Neurodevelopmental Disorders

Cited by 333

Integrative Modeling Defines the Nova Splicing-Regulatory Network and Its Combinatorial Controls

Zhang, C., Frias, M. A., Mele, A., Ruggiu, M., Eom, T., Marney, C. B., Wang, H., Licatalosi, D. D., Fak, J. J., & Darnell, R. B. (2010) · Science

RNA Research and SplicingRNA regulation and disease

Cited by 294

Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis

Moore, M. J., Zhang, C., Gantman, E. C., Mele, A., Darnell, J. C., & Darnell, R. B. (2014) · Nature Protocols

RNA Research and SplicingRNA regulation and disease

Cited by 251

Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability

Ince-Dunn, G., Okano, H. J., Jensen, K. B., Park, W.-Y., Zhong, R., Ule, J., Mele, A., Fak, J. J., Yang, C., Zhang, C., et al. (2012) · Neuron

RNA Research and SplicingNeuroscience and Neuropharmacology Research

Cited by 212

Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain

Licatalosi, D. D., Yano, M., Fak, J. J., Mele, A., Grabinski, S. E., Zhang, C., & Darnell, R. B. (2012) · Genes & Development

RNA Research and SplicingNeurogenesis and neuroplasticity mechanisms

Cited by 193

Nova2 Regulates Neuronal Migration through an RNA Switch in Disabled-1 Signaling

Yano, M., Hayakawa-Yano, Y., Mele, A., & Darnell, R. B. (2010) · Neuron

Neurogenesis and neuroplasticity mechanismsRNA Research and Splicing

Cited by 176