Korving, Jeroen

Identification of stem cells in small intestine and colon by marker gene Lgr5

Barker, N., van Es, J. H., Kuipers, J., Kujala, P., van den Born, M., Cozijnsen, M., Haegebarth, A., Korving, J., Begthel, H., Peters, P. J., et al. (2007) · Nature

Wnt/β-catenin signaling in development and cancerCancer Cells and Metastasis

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A living biobank of breast cancer organoids captures disease heterogeneity

Sachs, N., de Ligt, J., Kopper, O., Gogola, E., Bounova, G., Weeber, F., Balgobind, A. V., Wind, K., Gracanin, A., Begthel, H., et al. (2018) · Cell

Cancer Cells and MetastasisBreast Cancer Treatment Studies

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Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

Barker, N., Huch, M., Kujala, P., van de Wetering, M., Snippert, H. J., van Es, J. H., Sato, T., Stange, D. E., Begthel, H., van den Born, M., et al. (2010) · Cell Stem Cell

Cancer Cells and MetastasisWnt/β-catenin signaling in development and cancer

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Long‐term expanding human airway organoids for disease modeling

Sachs, N., Papaspyropoulos, A., Zomer‐van Ommen, D. D., Heo, I., Böttinger, L., Klay, D., Weeber, F., Huelsz‐Prince, G., Iakobachvili, N., Amatngalim, G. D., et al. (2019) · The EMBO Journal

Cystic Fibrosis Research AdvancesNeonatal Respiratory Health Research

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Sequential cancer mutations in cultured human intestinal stem cells

Drost, J., van Jaarsveld, R. H., Ponsioen, B., Zimberlin, C., van Boxtel, R., Buijs, A., Sachs, N., Overmeer, R. M., Offerhaus, G. J., Begthel, H., et al. (2015) · Nature

Cancer Cells and MetastasisGenetic factors in colorectal cancer

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Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids

Hu, H., Gehart, H., Artegiani, B., LÖpez-Iglesias, C., Dekkers, F., Basak, O., van Es, J., Chuva de Sousa Lopes, S. M., Begthel, H., Korving, J., et al. (2018) · Cell

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

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An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

Kopper, O., de Witte, C. J., Lõhmussaar, K., Valle-Inclan, J. E., Hami, N., Kester, L., Balgobind, A. V., Korving, J., Proost, N., Begthel, H., et al. (2019) · Nature Medicine

Ovarian cancer diagnosis and treatmentCancer Cells and Metastasis

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Replacement of lost Lgr5-positive stem cells through plasticity of their enterocyte-lineage daughters

Tetteh, P. W., Basak, O., Farin, H. F., Wiebrands, K., Kretzschmar, K., Begthel, H., van den Born, M., Korving, J., de Sauvage, F., van Es, J. H., et al. (2016) · Cell stem cell

Digestive system and related healthWnt/β-catenin signaling in development and cancer

Cited by 575

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche

Farin, H. F., Jordens, I., Mosa, M. H., Basak, O., Korving, J., Tauriello, D. V. F., de Punder, K., Angers, S., Peters, P. J., Maurice, M. M., et al. (2016) · Nature

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

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Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy

Driehuis, E., Kolders, S., Spelier, S., Lõhmussaar, K., Willems, S. M., Devriese, L. A., de Bree, R., de Ruiter, E. J., Korving, J., Begthel, H., et al. (2019) · Cancer Discovery

Cancer Cells and MetastasisHead and Neck Cancer Studies

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Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancer

Lõhmussaar, K., Oka, R., Espejo Valle-Inclan, J., Smits, M. H. H., Wardak, H., Korving, J., Begthel, H., Proost, N., van de Ven, M., Kranenburg, O. W., et al. (2021) · Cell Stem Cell

Cervical Cancer and HPV ResearchCancer Cells and Metastasis

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Severe nasal clefting and abnormal embryonic apoptosis in Alx3/Alx4 double mutant mice

Beverdam, A., Brouwer, A., Reijnen, M., Korving, J., & Meijlink, F. (2001) · Development

Cleft Lip and Palate ResearchCraniofacial Disorders and Treatments

Cited by 170

Unbiased transcription factor CRISPR screen identifies ZNF800 as master repressor of enteroendocrine differentiation

Lin, L., DeMartino, J., Wang, D., van Son, G. J. F., van der Linden, R., Begthel, H., Korving, J., Andersson-Rolf, A., van den Brink, S., Lopez-Iglesias, C., et al. (2023) · Science

Developmental Biology and Gene RegulationDigestive system and related health

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