Klco, Jeffery M.

The origin and evolution of mutations in acute myeloid leukemia

Welch, J. S., Ley, T. J., Link, D. C., Miller, C. A., Larson, D. E., Koboldt, D. C., Wartman, L. D., Lamprecht, T. L., Liu, F., Xia, J., et al. (2012) · Cell

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 1,575

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia

Wong, T. N., Ramsingh, G., Young, A. L., Miller, C. A., Touma, W., Welch, J. S., Lamprecht, T. L., Shen, D., Hundal, J., Fulton, R. S., et al. (2015) · Nature

Acute Myeloid Leukemia ResearchMultiple and Secondary Primary Cancers

Cited by 892

Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist

Olenyuk, B. Z., Zhang, G.-J., Klco, J. M., Nickols, N. G., Kaelin, W. G., & Dervan, P. B. (2004) · Proceedings of the National Academy of Sciences

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

Cited by 219

Enforced differentiation of Dnmt3a-null bone marrow leads to failure with c-Kit mutations driving leukemic transformation

Celik, H., Mallaney, C., Kothari, A., Ostrander, E. L., Eultgen, E., Martens, A., Miller, C. A., Hundal, J., Klco, J. M., & Challen, G. A. (2015) · Blood

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 95

Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies

Cole, C. B., Russler-Germain, D. A., Ketkar, S., Verdoni, A. M., Smith, A. M., Bangert, C. V., Helton, N. M., Guo, M., Klco, J. M., O’Laughlin, S., et al. (2017) · Journal of Clinical Investigation

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 84

Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines

Nishiguchi, G., Mascibroda, L. G., Young, S. M., Caine, E. A., Abdelhamed, S., Kooijman, J. J., Miller, D. J., Das, S., McGowan, K., Mayasundari, A., et al. (2024) · Nature Communications

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 57

Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells

Capoccia, B. J., Lennerz, J. K. M., Bredemeyer, A. J., Klco, J. M., Frater, J. L., & Mills, J. C. (2011) · Physiological Genomics

Endoplasmic Reticulum Stress and DiseaseT-cell and B-cell Immunology

Cited by 33