Leonhardt, Heinrich

Induction of tumors in mice by genomic hypomethylation

Gaudet, F., Hodgson, J. G., Eden, A., Jackson-Grusby, L., Dausman, J., Gray, J. W., Leonhardt, H., & Jaenisch, R. (2003) · Science

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 1,499

Comparative Analysis of Single-Cell RNA Sequencing Methods

Ziegenhain, C., Vieth, B., Parekh, S., Reinius, B., Guillaumet-Adkins, A., Smets, M., Leonhardt, H., Heyn, H., Hellmann, I., & Enard, W. (2017) · Molecular Cell

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 1,494

Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

Spruijt, C. G., Gnerlich, F., Smits, A. H., Pfaffeneder, T., Jansen, P. W. T. C., Bauer, C., Münzel, M., Wagner, M., Müller, M., Khan, F., et al. (2013) · Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 973

LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation

Solovei, I., Wang, A. S., Thanisch, K., Schmidt, C. S., Krebs, S., Zwerger, M., Cohen, T. V., Devys, D., Foisner, R., Peichl, L., et al. (2013) · Cell

Nuclear Structure and FunctionGenomics and Chromatin Dynamics

Cited by 809

Heterochromatin drives compartmentalization of inverted and conventional nuclei

Falk, M., Feodorova, Y., Naumova, N., Imakaev, M., Lajoie, B. R., Leonhardt, H., Joffe, B., Dekker, J., Fudenberg, G., Solovei, I., et al. (2019) · Nature

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 646

cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders

Andreeva, L., Hiller, B., Kostrewa, D., Lässig, C., de Oliveira Mann, C. C., Jan Drexler, D., Maiser, A., Gaidt, M., Leonhardt, H., Hornung, V., et al. (2017) · Nature

interferon and immune responsesDNA and Nucleic Acid Chemistry

Cited by 511

Recruitment of DNA methyltransferase I to DNA repair sites

Mortusewicz, O., Schermelleh, L., Walter, J., Cardoso, M. C., & Leonhardt, H. (2005) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsEpigenetics and DNA Methylation

Cited by 380

Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation

Schermelleh, L., Haemmer, A., Spada, F., Rösing, N., Meilinger, D., Rothbauer, U., Cardoso, M. C., & Leonhardt, H. (2007) · Nucleic Acids Research

Epigenetics and DNA MethylationDNA Repair Mechanisms

Cited by 247

DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex

Gasparoni, G., Bultmann, S., Lutsik, P., Kraus, T. F. J., Sordon, S., Vlcek, J., Dietinger, V., Steinmaurer, M., Haider, M., Mulholland, C. B., et al. (2018) · Epigenetics & Chromatin

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 229

Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation

Ferry, L., Fournier, A., Tsusaka, T., Adelmant, G., Shimazu, T., Matano, S., Kirsh, O., Amouroux, R., Dohmae, N., Suzuki, T., et al. (2017) · Molecular Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 203

TET dioxygenases localize at splicing speckles and promote RNA splicing

Hastert, F. D., Weber, J., Bauer, C., Zhadan, A., Singh, D. N. D., Dix, T. C., Arnold, R., Bessonov, S., Soller, M., Leonhardt, H., et al. (2025) · Nucleus

RNA Research and SplicingRNA modifications and cancer

Cited by 5

TET dioxygenases localize at splicing speckles and promote RNA splicing

Hastert, F. D., Weber, J., Bauer, C., Zhadan, A., Singh, D. N. D., Dix, T. C., Arnold, R., Bessonov, S., Soller, M., Leonhardt, H., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory)

RNA Research and SplicingRNA modifications and cancer

Cited by 0