Chuai, Guohui

DeepCRISPR: Optimized CRISPR guide RNA design by deep learning

Chuai, G., Ma, H., Yan, J., Chen, M., Hong, N., Xue, D., Zhou, C., Zhu, C., Chen, K., Duan, B., et al. (2018) · Genome biology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 641

Pan-Peptide Meta Learning for T-cell receptor–antigen binding recognition

Gao, Y., Gao, Y., Fan, Y., Zhu, C., Wei, Z., Zhou, C., Chuai, G., Chen, Q., Zhang, H., & Liu, Q. (2023) · Nature Machine Intelligence

vaccines and immunoinformatics approachesT-cell and B-cell Immunology

Cited by 155

Benchmarking algorithms for generalizable single-cell perturbation response prediction

Wei, Z., Wang, Y., Gao, Y., Wang, S., Li, P., Si, D., Gao, Y., Wu, S., Li, D., Dong, K., et al. (2026) · Nature Methods

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 42

Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models

Li, W., Jiang, X., Wang, W., Hou, L., Cai, R., Li, Y., Gu, Q., Chen, Q., Ma, P., Tang, J., et al. (2024) · Nature Communications

CRISPR and Genetic EngineeringGenomics and Phylogenetic Studies

Cited by 21