Shi, Wei Q.

Oncometabolite succinate promotes angiogenesis by upregulating VEGF expression through GPR91-mediated STAT3 and ERK activation

Mu, X., Zhao, T., Xu, C., Shi, W., Geng, B., Shen, J., Zhang, C., Pan, J., Yang, J., Hu, S., et al. (2017) · Oncotarget

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 124

Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells

Head, S. A., Shi, W., Zhao, L., Gorshkov, K., Pasunooti, K., Chen, Y., Deng, Z., Li, R.-J., Shim, J. S., Tan, W., et al. (2015) · Proceedings of the National Academy of Sciences

PI3K/AKT/mTOR signaling in cancerAngiogenesis and VEGF in Cancer

Cited by 111

Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation

Zong, G., Hu, Z., O’Keefe, S., Tranter, D., Iannotti, M. J., Baron, L., Hall, B., Corfield, K., Paatero, A. O., Henderson, M. J., et al. (2019) · Journal of the American Chemical Society

Toxin Mechanisms and ImmunotoxinsCellular transport and secretion

Cited by 93

Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis

Head, S. A., Shi, W. Q., Yang, E. J., Nacev, B. A., Hong, S. Y., Pasunooti, K. K., Li, R.-J., Shim, J. S., & Liu, J. O. (2017) · ACS Chemical Biology

PI3K/AKT/mTOR signaling in cancerCancer, Lipids, and Metabolism

Cited by 82

Molecular mechanisms underlying mangiferin-induced apoptosis and cell cycle arrest in A549 human lung carcinoma cells

SHI, W., DENG, J., TONG, R., YANG, Y., HE, X., LV, J., WANG, H., DENG, S., QI, P., ZHANG, D., et al. (2016) · Molecular Medicine Reports

Mangiferin and Mango ExtractsNatural Compound Pharmacology Studies

Cited by 50

Novel Tetrazole-Containing Analogues of Itraconazole as Potent Antiangiogenic Agents with Reduced Cytochrome P450 3A4 Inhibition

Li, Y., Pasunooti, K. K., Li, R.-J., Liu, W., Head, S. A., Shi, W. Q., & Liu, J. O. (2018) · Journal of Medicinal Chemistry

Synthesis of Tetrazole DerivativesHeterocyclic Compound Synthesis and Bioactivity

Cited by 43

Posttranslational insertion of small membrane proteins by the bacterial signal recognition particle.

Steinberg, R., Origi, A., Natriashvili, A., Sarmah, P., Licheva, M., Walker, P. M., Kraft, C., High, S., Luirink, J., Shi, W. Q., et al. (2020) · PLOS Biology

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 34

Co-translational biogenesis of lipid droplet integral membrane proteins

Leznicki, P., Schneider, H. O., Harvey, J. V., Shi, W. Q., & High, S. (2022) · Journal of Cell Science

Lipid metabolism and biosynthesisCellular transport and secretion

Cited by 20