Ostrov, David A.

Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis

Graham, W. V., He, W., Marchiando, A. M., Zha, J., Singh, G., Li, H.-S., Biswas, A., Ong, M. L. D. M., Jiang, Z.-H., Choi, W., et al. (2019) · Nature Medicine

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Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells

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Virus-based gene therapy researchHemophilia Treatment and Research

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Human leukocyte antigen B∗14:01 and B∗35:01 are associated with trimethoprim-sulfamethoxazole induced liver injury

Li, Y., Phillips, E. J., Dellinger, A., Nicoletti, P., Schutte, R., Li, D., Ostrov, D. A., Fontana, R. J., Watkins, P. B., Stolz, A., et al. (2021) · Hepatology

Drug-Induced Hepatotoxicity and ProtectionDrug-Induced Adverse Reactions

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Targeting of the protein interaction site between FAK and IGF-1R

Zheng, D., Kurenova, E., Ucar, D., Golubovskaya, V., Magis, A., Ostrov, D., Cance, W. G., & Hochwald, S. N. (2009) · Biochemical and Biophysical Research Communications

Cell Adhesion Molecules ResearchProtein Kinase Regulation and GTPase Signaling

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Identification of Functional Genetic Components Modulating Toxicity Response to PFOS using Genome-wide CRISPR Screens in HepG2/C3A cells

Kim, C., Tagmount, A., Zhu, Z., Wilson, F., Li, D., Ostrov, D. A., Barbazuk, W. B., Bacher, R., & Vulpe, C. D. (2025) · Archives of Toxicology

Per- and polyfluoroalkyl substances researchToxic Organic Pollutants Impact

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Identification of functional genetic components modulating toxicity response to PFOS using genome-wide CRISPR screens in HepG2/C3A cells

Kim, C., Tagmount, A., Zhu, Z., Wilson, F., Li, D., Ostrov, D. A., Brad Barbazuk, W., Bacher, R., & Vulpe, C. D. (2026) · Archives of Toxicology

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