Carroll, Martin

The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

Ward, P. S., Patel, J., Wise, D. R., Abdel-Wahab, O., Bennett, B. D., Coller, H. A., Cross, J. R., Fantin, V. R., Hedvat, C. V., Perl, A. E., et al. (2010) · Cancer Cell

Acute Myeloid Leukemia ResearchCancer, Hypoxia, and Metabolism

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Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

Farge, T., Saland, E., de Toni, F., Aroua, N., Hosseini, M., Perry, R., Bosc, C., Sugita, M., Stuani, L., Fraisse, M., et al. (2017) · Cancer Discovery

Acute Myeloid Leukemia ResearchCancer, Hypoxia, and Metabolism

Cited by 912

Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia

McMahon, C. M., Ferng, T., Canaani, J., Wang, E. S., Morrissette, J. J. D., Eastburn, D. J., Pellegrino, M., Durruthy-Durruthy, R., Watt, C. D., Asthana, S., et al. (2019) · Cancer Discovery

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

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AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3

Wunderlich, M., Chou, F.-S., Link, K. A., Mizukawa, B., Perry, R. L., Carroll, M., & Mulloy, J. C. (2010) · Leukemia

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 415

Mapping the cellular biogeography of human bone marrow niches using single-cell transcriptomics and proteomic imaging

Bandyopadhyay, S., Duffy, M. P., Ahn, K. J., Sussman, J. H., Pang, M., Smith, D., Duncan, G., Zhang, I., Huang, J., Lin, Y., et al. (2024) · Cell

Single-cell and spatial transcriptomicsHematopoietic Stem Cell Transplantation

Cited by 300

Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR

Ranuncolo, S. M., Polo, J. M., Dierov, J., Singer, M., Kuo, T., Greally, J., Green, R., Carroll, M., & Melnick, A. (2007) · Nature Immunology

DNA Repair MechanismsT-cell and B-cell Immunology

Cited by 278

Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence

Duy, C., Li, M., Teater, M., Meydan, C., Garrett-Bakelman, F. E., Lee, T. C., Chin, C. R., Durmaz, C., Kawabata, K. C., Dhimolea, E., et al. (2021) · Cancer Discovery

Acute Myeloid Leukemia ResearchTelomeres, Telomerase, and Senescence

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Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming

Zhao, F., Mancuso, A., Bui, T. V., Tong, X., Gruber, J. J., Swider, C. R., Sanchez, P. V., Lum, J. J., Sayed, N., Melo, J. V., et al. (2010) · Oncogene

Chronic Myeloid Leukemia TreatmentsCancer, Hypoxia, and Metabolism

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BCR/ABL translocates to the nucleus and disrupts an ATR-dependent intra-S phase checkpoint

Dierov, J., Dierova, R., & Carroll, M. (2004) · Cancer Cell

Chronic Myeloid Leukemia TreatmentsDNA Repair Mechanisms

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