Engel, Christoph

Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

Kuchenbaecker, K. B., Hopper, J. L., Barnes, D. R., Phillips, K.-A., Mooij, T. M., Roos-Blom, M.-J., Jervis, S., van Leeuwen, F. E., Milne, R. L., Andrieu, N., et al. (2017) · JAMA

BRCA gene mutations in cancerMultiple and Secondary Primary Cancers

Cited by 2,954

Intensive insulin therapy and pentastarch resuscitation in severe sepsis

Brunkhorst, F. M., Engel, C., Bloos, F., Meier-Hellmann, A., Ragaller, M., Weiler, N., Moerer, O., Gruendling, M., Oppert, M., Grond, S., et al. (2008) · New England Journal of Medicine

Hyperglycemia and glycemic control in critically ill and hospitalized patientsSepsis Diagnosis and Treatment

Cited by 2,921

Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

Vasen, H. F. A., Blanco, I., Aktan-Collan, K., Gopie, J. P., Alonso, A., Aretz, S., Bernstein, I., Bertario, L., Burn, J., Capella, G., et al. (2013) · Gut

Genetic factors in colorectal cancerBRCA gene mutations in cancer

Cited by 746

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

Meindl, A., Hellebrand, H., Wiek, C., Erven, V., Wappenschmidt, B., Niederacher, D., Freund, M., Lichtner, P., Hartmann, L., Schaal, H., et al. (2010) · Nature Genetics

BRCA gene mutations in cancerDNA Repair Mechanisms

Cited by 743

Association of Type and Location of BRCA1 and BRCA2 Mutations With Risk of Breast and Ovarian Cancer

Rebbeck, T. R., Mitra, N., Wan, F., Sinilnikova, O. M., Healey, S., McGuffog, L., Mazoyer, S., Chenevix-Trench, G., Easton, D. F., Antoniou, A. C., et al. (2015) · JAMA

BRCA gene mutations in cancerMultiple and Secondary Primary Cancers

Cited by 521

Contralateral Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Graeser, M. K., Engel, C., Rhiem, K., Gadzicki, D., Bick, U., Kast, K., Froster, U. G., Schlehe, B., Bechtold, A., Arnold, N., et al. (2009) · Journal of Clinical Oncology

BRCA gene mutations in cancerMultiple and Secondary Primary Cancers

Cited by 314

Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock: A Randomized Clinical Trial

Bloos, F., Trips, E., Nierhaus, A., Briegel, J., Heyland, D. K., Jaschinski, U., Moerer, O., Weyland, A., Marx, G., Gründling, M., et al. (2016) · JAMA Internal Medicine

Sepsis Diagnosis and TreatmentVitamin C and Antioxidants Research

Cited by 268

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

EMBRACE, Kuchenbaecker, K. B., Collaborators, G. S., Breast Cancer Family Registry, HEBON, KConFab Investigators, Australian Cancer Study (Ovarian Cancer Investigators), Australian Ovarian Cancer Study Group, the Consortium of Investigators of Modifiers of BRCA1 and BRCA2, Ramus, S. J., et al. (2015) · Nature Genetics

BRCA gene mutations in cancerOvarian cancer diagnosis and treatment

Cited by 250

Impact of compliance with infection management guidelines on outcome in patients with severe sepsis: A prospective observational multi-center study.

Bloos, F., Thomas-Rüddel, D., Rüddel, H., Engel, C., Schwarzkopf, D., Marshall, J. C., Harbarth, S., Simon, P., Riessen, R., Keh, D., et al. (2014) · Critical Care

Sepsis Diagnosis and TreatmentAbdominal Surgery and Complications

Cited by 240

Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: A cluster randomized trial.

for the MEDUSA study group, Bloos, F., Rüddel, H., Thomas-Rüddel, D., Schwarzkopf, D., Pausch, C., Harbarth, S., Schreiber, T., Gründling, M., Marshall, J., et al. (2017) · Intensive Care Medicine

Sepsis Diagnosis and TreatmentHealth Policy Implementation Science

Cited by 200

Evaluating the performance of the breast cancer genetic risk models BOADICEA, IBIS, BRCAPRO and Claus for predicting BRCA1/2 mutation carrier probabilities: a study based on 7352 families from the German Hereditary Breast and Ovarian Cancer Consortium

Fischer, C., Kuchenbäcker, K., Engel, C., Zachariae, S., Rhiem, K., Meindl, A., Rahner, N., Dikow, N., Plendl, H., Debatin, I., et al. (2013) · Journal of Medical Genetics

BRCA gene mutations in cancerGenetic factors in colorectal cancer

Cited by 94

Social determinants and lifestyle factors for brain health: implications for risk reduction of cognitive decline and dementia

Röhr, S., Pabst, A., Baber, R., Engel, C., Glaesmer, H., Hinz, A., Schroeter, M. L., Witte, A. V., Zeynalova, S., Villringer, A., et al. (2022) · Scientific Reports

Dementia and Cognitive Impairment ResearchHealth disparities and outcomes

Cited by 92

Activating ERBB2/HER2 mutations indicate susceptibility to pan-HER inhibitors in Lynch and Lynch-like colorectal cancer

Kloth, M., Ruesseler, V., Engel, C., Koenig, K., Peifer, M., Mariotti, E., Kuenstlinger, H., Florin, A., Rommerscheidt-Fuss, U., Koitzsch, U., et al. (2016) · Gut

Genetic factors in colorectal cancerColorectal Cancer Treatments and Studies

Cited by 73

Association between mental demands at work and cognitive functioning in the general population – results of the health study of the Leipzig research center for civilization diseases (LIFE)

Then, F. S., Luck, T., Luppa, M., Arélin, K., Schroeter, M. L., Engel, C., Löffler, M., Thiery, J., Villringer, A., & Riedel-Heller, S. G. (2014) · Journal of Occupational Medicine and Toxicology

Workplace Health and Well-beingCognitive Abilities and Testing

Cited by 48

Testosterone imbalance may link depression and increased body weight in premenopausal women

Stanikova, D., Zsido, R. G., Luck, T., Pabst, A., Enzenbach, C., Bae, Y. J., Thiery, J., Ceglarek, U., Engel, C., Wirkner, K., et al. (2019) · Translational Psychiatry

Hormonal and reproductive studiesMenopause: Health Impacts and Treatments

Cited by 47

A patient-level meta-analysis of intensive glucose control in critically ill adults

Adigbli, D., Li, Y., Hammond, N., Chatoor, R., Devaux, A. G., Li, Q., Billot, L., Annane, D., Arabi, Y., Bilotta, F., et al. (2024) · NEJM Evidence

Hyperglycemia and glycemic control in critically ill and hospitalized patientsDiabetes Management and Research

Cited by 25

Simultaneous Mass Spectrometry-Based Apolipoprotein Profiling and Apolipoprotein E Phenotyping in Patients with ASCVD and Mild Cognitive Impairment

Begcevic Brkovic, I., Zöhrer, B., Scholz, M., Reinicke, M., Dittrich, J., Kamalsada, S., Baber, R., Beutner, F., Teren, A., Engel, C., et al. (2022) · Nutrients

Lipoproteins and Cardiovascular HealthMass Spectrometry Techniques and Applications

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