Voet, Thierry

Methods and applications for single-cell and spatial multi-omics

Vandereyken, K., Sifrim, A., Thienpont, B., & Voet, T. (2023) · Nature Reviews Genetics

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 1,244

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

de Bruin, E. C., McGranahan, N., Mitter, R., Salm, M., Wedge, D. C., Yates, L., Jamal-Hanjani, M., Shafi, S., Murugaesu, N., Rowan, A. J., et al. (2014) · Science

Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations

Cited by 1,117

Chromosome instability is common in human cleavage-stage embryos

Vanneste, E., Voet, T., Le Caignec, C., Ampe, M., Konings, P., Melotte, C., Debrock, S., Amyere, M., Vikkula, M., Schuit, F., et al. (2009) · Nature Medicine

Prenatal Screening and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 880

A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain

Davie, K., Janssens, J., Koldere, D., De Waegeneer, M., Pech, U., Kreft, Ł., Aibar, S., Makhzami, S., Christiaens, V., Bravo González-Blas, C., et al. (2018) · Cell

Single-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms

Cited by 840

Identification of region-specific astrocyte subtypes at single cell resolution

Batiuk, M. Y., Martirosyan, A., Wahis, J., de Vin, F., Marneffe, C., Kusserow, C., Koeppen, J., Viana, J. F., Oliveira, J. F., Voet, T., et al. (2020) · Nature Communications

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 805

Toward Minimal Residual Disease-Directed Therapy in Melanoma

Rambow, F., Rogiers, A., Marin-Bejar, O., Aibar, S., Femel, J., Dewaele, M., Karras, P., Brown, D., Chang, Y. H., Debiec-Rychter, M., et al. (2018) · Cell

Melanoma and MAPK PathwaysCancer Cells and Metastasis

Cited by 771

G&T-seq: parallel sequencing of single-cell genomes and transcriptomes

Macaulay, I. C., Haerty, W., Kumar, P., Li, Y. I., Hu, T. X., Teng, M. J., Goolam, M., Saurat, N., Coupland, P., Shirley, L. M., et al. (2015) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 750

Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity

Angermueller, C., Clark, S. J., Lee, H. J., Macaulay, I. C., Teng, M. J., Hu, T. X., Krueger, F., Smallwood, S. A., Ponting, C. P., Voet, T., et al. (2016) · Nature Methods

Epigenetics and DNA MethylationSingle-cell and spatial transcriptomics

Cited by 717

Mosaic Copy Number Variation in Human Neurons

McConnell, M. J., Lindberg, M. R., Brennand, K. J., Piper, J. C., Voet, T., Cowing-Zitron, C., Shumilina, S., Lasken, R. S., Vermeesch, J. R., Hall, I. M., et al. (2013) · Science

Genomic variations and chromosomal abnormalitiesCancer Genomics and Diagnostics

Cited by 551

Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos

Goolam, M., Scialdone, A., Graham, S. J. L., Macaulay, I. C., Jedrusik, A., Hupalowska, A., Voet, T., Marioni, J. C., & Zernicka-Goetz, M. (2016) · Cell

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 484

Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

Wilson, N. K., Kent, D. G., Buettner, F., Shehata, M., Macaulay, I. C., Calero-Nieto, F. J., Sánchez Castillo, M., Oedekoven, C. A., Diamanti, E., Schulte, R., et al. (2015) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationSingle-cell and spatial transcriptomics

Cited by 466

Single-cell multiomics: multiple measurements from single cells

Macaulay, I. C., Ponting, C. P., & Voet, T. (2017) · Trends in Genetics

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 451

Single Cell Genomics: Advances and Future Perspectives

Macaulay, I. C., & Voet, T. (2014) · PLoS Genetics

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 384

A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma

Pozniak, J., Pedri, D., Landeloos, E., Van Herck, Y., Antoranz, A., Vanwynsberghe, L., Nowosad, A., Roda, N., Makhzami, S., Bervoets, G., et al. (2024) · Cell

Cancer Immunotherapy and BiomarkersMelanoma and MAPK Pathways

Cited by 199

Single-Cell RNA-Sequencing Reveals a Continuous Spectrum of Differentiation in Hematopoietic Cells

Macaulay, I. C., Svensson, V., Labalette, C., Ferreira, L., Hamey, F., Voet, T., Teichmann, S. A., & Cvejic, A. (2016) · Cell Reports

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 191

Tissue damage induces a conserved stress response that initiates quiescent muscle stem cell activation

Machado, L., Geara, P., Camps, J., Dos Santos, M., Teixeira-Clerc, F., Van Herck, J., Varet, H., Legendre, R., Pawlotsky, J.-M., Sampaolesi, M., et al. (2021) · Cell Stem Cell

Muscle Physiology and DisordersSingle-cell and spatial transcriptomics

Cited by 170

On the identification of low allele frequency mosaic mutations in the brains of Alzheimer’s disease patients

Sala Frigerio, C., Lau, P., Troakes, C., Deramecourt, V., Gele, P., Van Loo, P., Voet, T., & De Strooper, B. (2015) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 71