Dees, Clara

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

Akhmetshina, A., Palumbo, K., Dees, C., Bergmann, C., Venalis, P., Zerr, P., Horn, A., Kireva, T., Beyer, C., Zwerina, J., et al. (2012) · Nature Communications

TGF-β signaling in diseasesWnt/β-catenin signaling in development and cancer

Cited by 843

Platelet-derived serotonin links vascular disease and tissue fibrosis

Dees, C., Akhmetshina, A., Zerr, P., Reich, N., Palumbo, K., Horn, A., Jüngel, A., Beyer, C., Krönke, G., Zwerina, J., et al. (2011) · Journal of Experimental Medicine

Systemic Sclerosis and Related DiseasesTGF-β signaling in diseases

Cited by 266

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis

Beyer, C., Schramm, A., Akhmetshina, A., Dees, C., Kireva, T., Gelse, K., Sonnylal, S., de Crombrugghe, B., Taketo, M. M., Distler, O., et al. (2012) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesTGF-β signaling in diseases

Cited by 203

Dual inhibition of c-abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis

Akhmetshina, A., Dees, C., Pileckyte, M., Maurer, B., Axmann, R., Jüngel, A., Zwerina, J., Gay, S., Schett, G., Distler, O., et al. (2008) · The FASEB Journal

Systemic Sclerosis and Related DiseasesDupuytren's Contracture and Treatments

Cited by 187

PU.1 controls fibroblast polarization and tissue fibrosis

Wohlfahrt, T., Rauber, S., Uebe, S., Luber, M., Soare, A., Ekici, A., Weber, S., Matei, A.-E., Chen, C.-W., Maier, C., et al. (2019) · Nature

TGF-β signaling in diseasesLiver physiology and pathology

Cited by 187

The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis

Reich, N., Maurer, B., Akhmetshina, A., Venalis, P., Dees, C., Zerr, P., Palumbo, K., Zwerina, J., Nevskaya, T., Gay, S., et al. (2010) · Arthritis & Rheumatism

Systemic Sclerosis and Related DiseasesDupuytren's Contracture and Treatments

Cited by 112

Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis

Krämer, M., Dees, C., Huang, J., Schlottmann, I., Palumbo-Zerr, K., Zerr, P., Gelse, K., Beyer, C., Distler, A., Marquez, V. E., et al. (2013) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesDupuytren's Contracture and Treatments

Cited by 109

Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis

Zhang, Y., Dees, C., Beyer, C., Lin, N.-Y., Distler, A., Zerr, P., Palumbo, K., Susok, L., Kreuter, A., Distler, O., et al. (2015) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesTGF-β signaling in diseases

Cited by 64

The histone demethylase Jumonji domain-containing protein 3 (JMJD3) regulates fibroblast activation in systemic sclerosis

Bergmann, C., Brandt, A., Merlevede, B., Hallenberger, L., Dees, C., Wohlfahrt, T., Pötter, S., Zhang, Y., Chen, C.-W., Mallano, T., et al. (2018) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesTGF-β signaling in diseases

Cited by 62