Gattinoni, Luca

A human memory T cell subset with stem cell–like properties

Gattinoni, L., Lugli, E., Ji, Y., Pos, Z., Paulos, C. M., Quigley, M. F., Almeida, J. R., Gostick, E., Yu, Z., Carpenito, C., et al. (2011) · Nature Medicine

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 1,974

Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

Gattinoni, L., Zhong, X.-S., Palmer, D. C., Ji, Y., Hinrichs, C. S., Yu, Z., Wrzesinski, C., Boni, A., Cassard, L., Garvin, L. M., et al. (2009) · Nature Medicine

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 1,031

Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function

Sukumar, M., Liu, J., Ji, Y., Subramanian, M., Crompton, J. G., Yu, Z., Roychoudhuri, R., Palmer, D. C., Muranski, P., Karoly, E. D., et al. (2013) · Journal of Clinical Investigation

T-cell and B-cell ImmunologyCancer, Hypoxia, and Metabolism

Cited by 952

Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling

Paulos, C. M., Wrzesinski, C., Kaiser, Hinrichs, C. S., Chieppa, M., Cassard, L., Palmer, D. C., Boni, A., Muranski, P., Yu, Z., et al. (2007) · Journal of Clinical Investigation

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 586

Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection

Yao, C., Sun, H.-W., Lacey, N. E., Ji, Y., Moseman, E. A., Shih, H.-Y., Heuston, E. F., Kirby, M., Anderson, S., Cheng, J., et al. (2019) · Nature Immunology

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 549

CD8 + T‐cell memory in tumor immunology and immunotherapy

Klebanoff, C. A., Gattinoni, L., & Restifo, N. P. (2006) · Immunological Reviews

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 511

Th17 cells are long lived and retain a stem cell-like molecular signature

Muranski, P., Borman, Z. A., Kerkar, S. P., Klebanoff, C. A., Ji, Y., Sanchez-Perez, L., Sukumar, M., Reger, R. N., Yu, Z., Kern, S. J., et al. (2011) · Immunity

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 443

Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans

Galletti, G., De Simone, G., Mazza, E. M. C., Puccio, S., Mezzanotte, C., Bi, T. M., Davydov, A. N., Metsger, M., Scamardella, E., Alvisi, G., et al. (2020) · Nature Immunology

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 299

High-Efficiency Transfection of Primary Human and Mouse T Lymphocytes Using RNA Electroporation

Zhao, Y., Zheng, Z., Cohen, C. J., Gattinoni, L., Palmer, D. C., Restifo, N. P., Rosenberg, S. A., & Morgan, R. A. (2006) · Molecular Therapy

Microbial Inactivation MethodsRNA Interference and Gene Delivery

Cited by 283

Regulation of nucleosome landscape and transcription factor targeting at tissue-specific enhancers by BRG1

Hu, G., Schones, D. E., Cui, K., Ybarra, R., Northrup, D., Tang, Q., Gattinoni, L., Restifo, N. P., Huang, S., & Zhao, K. (2011) · Genome Research

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 186

T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy

Yamamoto, T. N., Lee, P.-H., Vodnala, S. K., Gurusamy, D., Kishton, R. J., Yu, Z., Eidizadeh, A., Eil, R., Fioravanti, J., Gattinoni, L., et al. (2019) · Journal of Clinical Investigation

CAR-T cell therapy researchImmunotherapy and Immune Responses

Cited by 156

CXCR3 Identifies Human Naive CD8+ T Cells with Enhanced Effector Differentiation Potential

De Simone, G., Mazza, E. M. C., Cassotta, A., Davydov, A. N., Kuka, M., Zanon, V., De Paoli, F., Scamardella, E., Metsger, M., Roberto, A., et al. (2019) · The Journal of Immunology

T-cell and B-cell ImmunologyChemokine receptors and signaling

Cited by 49