Bradshaw, Elizabeth M.

Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

Olah, M., Menon, V., Habib, N., Taga, M. F., Ma, Y., Yung, C. J., Cimpean, M., Khairallah, A., Coronas-Samano, G., Sankowski, R., et al. (2020) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 722

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

Initiative, T. A. D. N., Bradshaw, E. M., Chibnik, L. B., Keenan, B. T., Ottoboni, L., Raj, T., Tang, A., Rosenkrantz, L. L., Imboywa, S., Lee, M., et al. (2013) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 570

A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease

Mostafavi, S., Gaiteri, C., Sullivan, S. E., White, C. C., Tasaki, S., Xu, J., Taga, M., Klein, H.-U., Patrick, E., Komashko, V., et al. (2018) · Nature Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 509

IL-9 induces differentiation of T H 17 cells and enhances function of FoxP3 + natural regulatory T cells

Elyaman, W., Bradshaw, E. M., Uyttenhove, C., Dardalhon, V., Awasthi, A., Imitola, J., Bettelli, E., Oukka, M., van Snick, J., Renauld, J.-C., et al. (2009) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 498

A transcriptomic atlas of aged human microglia

Olah, M., Patrick, E., Villani, A.-C., Xu, J., White, C. C., Ryan, K. J., Piehowski, P., Kapasi, A., Nejad, P., Cimpean, M., et al. (2018) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 482

Neuropathological correlates and genetic architecture of microglial activation in elderly human brain

Felsky, D., Roostaei, T., Nho, K., Risacher, S. L., Bradshaw, E. M., Petyuk, V., Schneider, J. A., Saykin, A., Bennett, D. A., & De Jager, P. L. (2019) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 169

CD33 modulates TREM2: convergence of Alzheimer loci

Chan, G., White, C. C., Winn, P. A., Cimpean, M., Replogle, J. M., Glick, L. R., Cuerdon, N. E., Ryan, K. J., Johnson, K. A., Schneider, J. A., et al. (2015) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 162

CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer’s disease susceptibility

Raj, T., Ryan, K. J., Replogle, J. M., Chibnik, L. B., Rosenkrantz, L., Tang, A., Rothamel, K., Stranger, B. E., Bennett, D. A., Evans, D. A., et al. (2014) · Human Molecular Genetics

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 144

BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology

Taga, M., Petyuk, V. A., White, C., Marsh, G., Ma, Y., Klein, H.-U., Connor, S. M., Kroshilina, A., Yung, C. J., Khairallah, A., et al. (2020) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 81

A cortical immune network map identifies a subset of human microglia involved in Tau pathology

Patrick, E., Olah, M., Taga, M., Klein, H.-U., Xu, J., White, C. C., Felsky, D., Gaiteri, C., Chibnik, L. B., Mostafavi, S., et al. (2017) · Translational Psychiatry

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 39

A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies

Patrick, E., Olah, M., Taga, M., Klein, H.-U., Xu, J., White, C. C., Felsky, D., Agrawal, S., Gaiteri, C., Chibnik, L. B., et al. (2021) · Translational Psychiatry

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 31