Yu, Je-Wook

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

Fernandes-Alnemri, T., Yu, J.-W., Datta, P., Wu, J., & Alnemri, E. S. (2009) · Nature

Inflammasome and immune disordersinterferon and immune responses

Cited by 1,831

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

Fernandes-Alnemri, T., Wu, J., Yu, J.-W., Datta, P., Miller, B., Jankowski, W., Rosenberg, S., Zhang, J., & Alnemri, E. S. (2007) · Cell Death & Differentiation

Inflammasome and immune disordersCell death mechanisms and regulation

Cited by 1,026

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

Fernandes-Alnemri, T., Yu, J.-W., Juliana, C., Solorzano, L., Kang, S., Wu, J., Datta, P., McCormick, M., Huang, L., McDermott, E., et al. (2010) · Nature Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 732

MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration

Lee, E., Hwang, I., Park, S., Hong, S., Hwang, B., Cho, Y., Son, J., & Yu, J.-W. (2019) · Cell Death & Differentiation

Inflammasome and immune disordersParkinson's Disease Mechanisms and Treatments

Cited by 431

Rotenone-induced Impairment of Mitochondrial Electron Transport Chain Confers a Selective Priming Signal for NLRP3 Inflammasome Activation

Won, J.-H., Park, S., Hong, S., Son, S., & Yu, J.-W. (2015) · Journal of Biological Chemistry

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 142

SGK1 inhibition in glia ameliorates pathologies and symptoms in Parkinson disease animal models

Kwon, O., Song, J., Yang, Y., Kim, S., Kim, J. Y., Seok, M., Hwang, I., Yu, J., Karmacharya, J., Maeng, H., et al. (2021) · EMBO Molecular Medicine

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 110

NLRP3 Inflammasome Contributes to Lipopolysaccharide-induced Depressive-Like Behaviors via Indoleamine 2,3-dioxygenase Induction

Jeon, S.-A., Lee, E., Hwang, I., Han, B., Park, S., Son, S., Yang, J., Hong, S., Kim, C. H., Son, J., et al. (2017) · International Journal of Neuropsychopharmacology

Tryptophan and brain disordersInflammasome and immune disorders

Cited by 62

Intracellular NAD+ Depletion Confers a Priming Signal for NLRP3 Inflammasome Activation

Shim, D.-W., Cho, H.-J., Hwang, I., Jung, T.-Y., Kim, H.-S., Ryu, J. H., & Yu, J.-W. (2021) · Frontiers in Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 24