Najafov, Ayaz

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS

Ito, Y., Ofengeim, D., Najafov, A., Das, S., Saberi, S., Li, Y., Hitomi, J., Zhu, H., Chen, H., Mayo, L., et al. (2016) · Science

Amyotrophic Lateral Sclerosis ResearchCell death mechanisms and regulation

Cited by 606

Activation of Necroptosis in Multiple Sclerosis

Ofengeim, D., Ito, Y., Najafov, A., Zhang, Y., Shan, B., DeWitt, J. P., Ye, J., Zhang, X., Chang, A., Vakifahmetoglu-Norberg, H., et al. (2015) · Cell Reports

Cell death mechanisms and regulationMultiple Sclerosis Research Studies

Cited by 526

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis

Geng, J., Ito, Y., Shi, L., Amin, P., Chu, J., Ouchida, A. T., Mookhtiar, A. K., Zhao, H., Xu, D., Shan, B., et al. (2017) · Nature Communications

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 325

Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model

Xu, X., Sun, Y., Cen, X., Shan, B., Zhao, Q., Xie, T., Wang, Z., Hou, T., Xue, Y., Zhang, M., et al. (2021) · Protein & Cell

Autophagy in Disease and TherapyAlzheimer's disease research and treatments

Cited by 171

ARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation

Wu, Y., Zhang, C., Liu, X., He, Z., Shan, B., Zeng, Q., Zhao, Q., Zhu, H., Liao, H., Cen, X., et al. (2021) · Nature Communications

Cancer Immunotherapy and BiomarkersUbiquitin and proteasome pathways

Cited by 117