Loregger, Anke

Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism

Loregger, A., Raaben, M., Nieuwenhuis, J., Tan, J. M. E., Jae, L. T., van den Hengel, L. G., Hendrix, S., van den Berg, M., Scheij, S., Song, J.-Y., et al. (2020) · Nature Communications

Cancer, Lipids, and MetabolismCholesterol and Lipid Metabolism

Cited by 51

Identification of the (Pro)renin Receptor as a Novel Regulator of Low-Density Lipoprotein Metabolism

Lu, X., Meima, M. E., Nelson, J. K., Sorrentino, V., Loregger, A., Scheij, S., Dekkers, D. H. W., Mulder, M. T., Demmers, J. A. A., M-Dallinga-Thie, G., et al. (2016) · Circulation Research

Renin-Angiotensin System StudiesCholesterol and Lipid Metabolism

Cited by 48

A MARCH6 and IDOL E3 Ubiquitin Ligase Circuit Uncouples Cholesterol Synthesis from Lipoprotein Uptake in Hepatocytes

Loregger, A., Cook, E. C. L., Nelson, J. K., Moeton, M., Sharpe, L. J., Engberg, S., Karimova, M., Lambert, G., Brown, A. J., & Zelcer, N. (2016) · Molecular and Cellular Biology

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 48

Hepatic SREBP signaling requires SPRING to govern systemic lipid metabolism in mice and humans

Hendrix, S., Kingma, J., Ottenhoff, R., Valiloo, M., Svecla, M., Zijlstra, L. F., Sachdev, V., Kovac, K., Levels, J. H. M., Jongejan, A., et al. (2023) · Nature Communications

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 34

SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P

Hendrix, S., Tan, J. M. E., Ndoj, K., Kingma, J., Valiloo, M., Zijlstra, L. F., Ottenhoff, R., Seidah, N. G., Loregger, A., Kober, D. L., et al. (2024) · Molecular and Cellular Biology

Sphingolipid Metabolism and SignalingLipid metabolism and biosynthesis

Cited by 9