Zheng, Wei

Macrophage models of Gaucher disease for evaluating disease pathogenesis and candidate drugs

Aflaki, E., Stubblefield, B. K., Maniwang, E., Lopez, G., Moaven, N., Goldin, E., Marugan, J., Patnaik, S., Dutra, A., Southall, N., et al. (2014) · Science Translational Medicine

Lysosomal Storage Disorders ResearchGlycogen Storage Diseases and Myoclonus

Cited by 126

Collaborative Development of 2-Hydroxypropyl-β-Cyclodextrin for the Treatment of Niemann-Pick Type C1 Disease

Ottinger, E., Kao, M., Carrillo-Carrasco, N., Yanjanin, N., Shankar, R., Janssen, M., Brewster, M., Scott, I., Xu, X., Cradock, J., et al. (2014) · Current Topics in Medicinal Chemistry

Lysosomal Storage Disorders ResearchGlycogen Storage Diseases and Myoclonus

Cited by 121

Drug discovery and development for rare genetic disorders

Sun, W., Zheng, W., & Simeonov, A. (2017) · American Journal of Medical Genetics Part A

Genomics and Rare DiseasesComputational Drug Discovery Methods

Cited by 107

Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors

Capuzzi, S. J., Sun, W., Muratov, E. N., Martínez-Romero, C., He, S., Zhu, W., Li, H., Tawa, G., Fisher, E. G., Xu, M., et al. (2018) · Journal of Medicinal Chemistry

Viral Infections and Outbreaks ResearchComputational Drug Discovery Methods

Cited by 35

A High-Throughput Screening Assay for Fungicidal Compounds against Cryptococcus neoformans

Rabjohns, J. L. A., Park, Y.-D., Dehdashti, J., Sun, W., Henderson, C., Zelazny, A., Metallo, S. J., Zheng, W., & Williamson, P. R. (2014) · SLAS Discovery

Fungal Infections and StudiesAntifungal resistance and susceptibility

Cited by 33

Identification of small-molecule agonists of human relaxin family receptor 1 (RXFP1) by using a homogenous cell-based cAMP assay

Chen, C. Z., Southall, N., Xiao, J., Marugan, J. J., Ferrer, M., Hu, X., Jones, R. E., Feng, S., Agoulnik, I. U., Zheng, W., et al. (2013) · SLAS Discovery

Pregnancy-related medical researchReceptor Mechanisms and Signaling

Cited by 31

Evaluation of Cholesterol Reduction Activity of Methyl-β-cyclodextrin Using Differentiated Human Neurons and Astrocytes

Swaroop, M., Thorne, N., Rao, M. S., Austin, C. P., McKew, J. C., & Zheng, W. (2012) · SLAS Discovery

Lysosomal Storage Disorders ResearchCholesterol and Lipid Metabolism

Cited by 22

Analytical Characterization of Methyl-β-Cyclodextrin for Pharmacological Activity to Reduce Lysosomal Cholesterol Accumulation in Niemann-Pick Disease Type C1 Cells

Li, R., Hao, J., Fujiwara, H., Xu, M., Yang, S., Dai, S., Long, Y., Swaroop, M., Li, C., Vu, M., et al. (2017) · ASSAY and Drug Development Technologies

Lysosomal Storage Disorders ResearchBiomedical Research and Pathophysiology

Cited by 21