Eklund, Lauri

Therapeutic targeting of the angiopoietin–TIE pathway

Saharinen, P., Eklund, L., & Alitalo, K. (2017) · Nature Reviews Drug Discovery

Angiogenesis and VEGF in CancerLymphatic System and Diseases

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Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell–cell and cell–matrix contacts

Saharinen, P., Eklund, L., Miettinen, J., Wirkkala, R., Anisimov, A., Winderlich, M., Nottebaum, A., Vestweber, D., Deutsch, U., Koh, G. Y., et al. (2008) · Nature Cell Biology

Angiogenesis and VEGF in CancerLymphatic System and Diseases

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Endothelial destabilization by angiopoietin-2 via integrin β1 activation

Hakanpaa, L., Sipila, T., Leppanen, V.-M., Gautam, P., Nurmi, H., Jacquemet, G., Eklund, L., Ivaska, J., Alitalo, K., & Saharinen, P. (2015) · Nature Communications

Angiogenesis and VEGF in CancerCell Adhesion Molecules Research

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Effects of Angiopoietin-2-Blocking Antibody on Endothelial Cell–Cell Junctions and Lung Metastasis

Holopainen, T., Saharinen, P., D’Amico, G., Lampinen, A., Eklund, L., Sormunen, R., Anisimov, A., Zarkada, G., Lohela, M., Heloterä, H., et al. (2012) · JNCI: Journal of the National Cancer Institute

Angiogenesis and VEGF in CancerLymphatic System and Diseases

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Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression

Korhonen, E. A., Murtomäki, A., Jha, S. K., Anisimov, A., Pink, A., Zhang, Y., Stritt, S., Liaqat, I., Stanczuk, L., Alderfer, L., et al. (2022) · Journal of Clinical Investigation

Lymphatic System and DiseasesAngiogenesis and VEGF in Cancer

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Targeting β1-integrin inhibits vascular leakage in endotoxemia

Hakanpaa, L., Kiss, E. A., Jacquemet, G., Miinalainen, I., Lerche, M., Guzmán, C., Mervaala, E., Eklund, L., Ivaska, J., & Saharinen, P. (2018) · Proceedings of the National Academy of Sciences

Cell Adhesion Molecules ResearchBarrier Structure and Function Studies

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