DePeaux, Kristin

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

Scharping, N. E., Rivadeneira, D. B., Menk, A. V., Vignali, P. D. A., Ford, B. R., Rittenhouse, N. L., Peralta, R., Wang, Y., Wang, Y., DePeaux, K., et al. (2021) · Nature Immunology

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

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Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

Vignali, P. D. A., DePeaux, K., Watson, M. J., Ye, C., Ford, B. R., Lontos, K., McGaa, N. K., Scharping, N. E., Menk, A. V., Robson, S. C., et al. (2023) · Nature Immunology

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

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Tumor hypoxia is associated with resistance to PD-1 blockade in squamous cell carcinoma of the head and neck

Zandberg, D. P., Menk, A. V., Velez, M., Normolle, D., DePeaux, K., Liu, A., Ferris, R. L., & Delgoffe, G. M. (2021) · Journal for ImmunoTherapy of Cancer

Cancer Immunotherapy and BiomarkersCancer, Hypoxia, and Metabolism

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