Calderwood, Michael A.

A reference map of the human binary protein interactome

Luck, K., Kim, D.-K., Lambourne, L., Spirohn, K., Begg, B. E., Bian, W., Brignall, R., Cafarelli, T., Campos-Laborie, F. J., Charloteaux, B., et al. (2020) · Nature

Bioinformatics and Genomic NetworksAdvanced Proteomics Techniques and Applications

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Proto-genes and de novo gene birth

Carvunis, A.-R., Rolland, T., Wapinski, I., Calderwood, M. A., Yildirim, M. A., Simonis, N., Charloteaux, B., Hidalgo, C. A., Barbette, J., Santhanam, B., et al. (2012) · Nature

Chromosomal and Genetic VariationsEvolution and Genetic Dynamics

Cited by 669

Widespread macromolecular interaction perturbations in human genetic disorders

Sahni, N., Yi, S., Taipale, M., Fuxman Bass, J. I., Coulombe-Huntington, J., Yang, F., Peng, J., Weile, J., Karras, G. I., Wang, Y., et al. (2015) · Cell

Genomics and Rare DiseasesBioinformatics and Genomic Networks

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Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

Yang, X., Coulombe-Huntington, J., Kang, S., Sheynkman, G. M., Hao, T., Richardson, A., Sun, S., Yang, F., Shen, Y. A., Murray, R. R., et al. (2016) · Cell

RNA Research and SplicingBioinformatics and Genomic Networks

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Epstein–Barr virus and virus human protein interaction maps

Calderwood, M. A., Venkatesan, K., Xing, L., Chase, M. R., Vazquez, A., Holthaus, A. M., Ewence, A. E., Li, N., Hirozane-Kishikawa, T., Hill, D. E., et al. (2007) · Proceedings of the National Academy of Sciences

Viral-associated cancers and disordersCytomegalovirus and herpesvirus research

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Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins

Rozenblatt-Rosen, O., Deo, R. C., Padi, M., Adelmant, G., Calderwood, M. A., Rolland, T., Grace, M., Dricot, A., Askenazi, M., Tavares, M., et al. (2012) · Nature

Bioinformatics and Genomic NetworksViral-associated cancers and disorders

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Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

Corominas, R., Yang, X., Lin, G. N., Kang, S., Shen, Y., Ghamsari, L., Broly, M., Rodriguez, M., Tam, S., Wanamaker, S. A., et al. (2014) · Nature Communications

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

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Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms

Lambourne, L., Mattioli, K., Santoso, C., Sheynkman, G., Inukai, S., Kaundal, B., Berenson, A., Spirohn-Fitzgerald, K., Bhattacharjee, A., Rothman, E., et al. (2025) · Molecular Cell

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

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AI-guided pipeline for protein–protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

Trepte, P., Secker, C., Olivet, J., Blavier, J., Kostova, S., Maseko, S. B., Minia, I., Silva Ramos, E., Cassonnet, P., Golusik, S., et al. (2024) · Molecular Systems Biology

Computational Drug Discovery MethodsSARS-CoV-2 and COVID-19 Research

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EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling

Randzavola, L. O., Mortimer, P. M., Garside, E., Dufficy, E. R., Schejtman, A., Roumelioti, G., Yu, L., Pardo, M., Spirohn, K., Tolley, C., et al. (2022) · eLife

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune Disorders

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EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling

Randzavola, L. O., Mortimer, P. M., Garside, E., Dufficy, E. R., Schejtman, A., Roumelioti, G., Yu, L., Pardo, M., Spirohn, K., Tolley, C., et al. (2021) · eLife

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune Disorders

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