Kaku, Kohei

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

Unoki, H., Takahashi, A., Kawaguchi, T., Hara, K., Horikoshi, M., Andersen, G., Ng, D. P. K., Holmkvist, J., Borch-Johnsen, K., Jørgensen, T., et al. (2008) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 725

Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial

Ueki, K., Sasako, T., Okazaki, Y., Kato, M., Okahata, S., Katsuyama, H., Haraguchi, M., Morita, A., Ohashi, K., Hara, K., et al. (2017) · The Lancet Diabetes & Endocrinology

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 313

Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance

Kawamori, R., Tajima, N., Iwamoto, Y., Kashiwagi, A., Shimamoto, K., & Kaku, K. (2009) · The Lancet

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 303

GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation

Shigeto, M., Ramracheya, R., Tarasov, A. I., Cha, C. Y., Chibalina, M. V., Hastoy, B., Philippaert, K., Reinbothe, T., Rorsman, N., Salehi, A., et al. (2015) · Journal of Clinical Investigation

Pancreatic function and diabetesIon Channels and Receptors

Cited by 189

Factors affecting canagliflozin-induced transient urine volume increase in patients with type 2 diabetes mellitus

Tanaka, H., Takano, K., Iijima, H., Kubo, H., Maruyama, N., Hashimoto, T., Arakawa, K., Togo, M., Inagaki, N., & Kaku, K. (2017) · Advances in Therapy

Diabetes Treatment and ManagementHeart Failure Treatment and Management

Cited by 140

Safety and efficacy of once‐weekly semaglutide vs additional oral antidiabetic drugs in Japanese people with inadequately controlled type 2 diabetes: A randomized trial

Kaku, K., Yamada, Y., Watada, H., Abiko, A., Nishida, T., Zacho, J., & Kiyosue, A. (2018) · Diabetes, Obesity and Metabolism

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 132

Structural and functional analysis of pancreatic islets preserved by pioglitazone in db/db mice

Kawasaki, F., Matsuda, M., Kanda, Y., Inoue, H., & Kaku, K. (2005) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 99

The relationship between fasting hyperglycemia and insulin secretion in subjects with normal or impaired glucose tolerance

Abdul-Ghani, M. A., Matsuda, M., Jani, R., Jenkinson, C. P., Coletta, D. K., Kaku, K., & DeFronzo, R. A. (2008) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 91

Molecular mechanism by which pioglitazone preserves pancreatic β-cells in obese diabetic mice: evidence for acute and chronic actions as a PPARγ agonist

Kanda, Y., Shimoda, M., Hamamoto, S., Tawaramoto, K., Kawasaki, F., Hashiramoto, M., Nakashima, K., Matsuki, M., & Kaku, K. (2010) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesPeroxisome Proliferator-Activated Receptors

Cited by 63

Safety and efficacy of the sodium-glucose cotransporter 1 inhibitor mizagliflozin for functional constipation: a randomised, placebo-controlled, double-blind phase 2 trial

Fukudo, S., Endo, Y., Hongo, M., Nakajima, A., Abe, T., Kobayashi, H., Nakata, T., Nakajima, T., Sameshima, K., Kaku, K., et al. (2018) · The Lancet Gastroenterology & Hepatology

Gastrointestinal motility and disordersPelvic floor disorders treatments

Cited by 50

Sitagliptin improves glycaemic excursion after a meal or after an oral glucose load in Japanese subjects with impaired glucose tolerance

Kaku, K., Kadowaki, T., Terauchi, Y., Okamoto, T., Sato, A., Okuyama, K., Arjona Ferreira, J. C., & Goldstein, B. J. (2015) · Diabetes, Obesity and Metabolism

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 22

Safety and efficacy of the combination of the glucagon‐like peptide‐1 receptor agonist liraglutide with an oral antidiabetic drug in Japanese patients with type 2 diabetes: Post‐hoc analysis of a randomized, 52‐week, open‐label, parallel‐group trial

Kiyosue, A., Seino, Y., Nishijima, K., Bosch‐Traberg, H., & Kaku, K. (2018) · Journal of Diabetes Investigation

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 5