Davies, Janet E.

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Ravikumar, B., Vacher, C., Berger, Z., Davies, J. E., Luo, S., Oroz, L. G., Scaravilli, F., Easton, D. F., Duden, R., O'Kane, C. J., et al. (2004) · Nature Genetics

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

Cited by 2,347

Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein

Sarkar, S., Davies, J. E., Huang, Z., Tunnacliffe, A., & Rubinsztein, D. C. (2007) · Journal of Biological Chemistry

Autophagy in Disease and TherapyGenetic Neurodegenerative Diseases

Cited by 1,142

Huntington's disease: from pathology and genetics to potential therapies

Imarisio, S., Carmichael, J., Korolchuk, V., Chen, C.-W., Saiki, S., Rose, C., Krishna, G., Davies, J. E., Ttofi, E., Underwood, B. R., et al. (2008) · Biochemical Journal

Genetic Neurodegenerative DiseasesGenetics and Neurodevelopmental Disorders

Cited by 409

Trehalose reduces aggregate formation and delays pathology in a transgenic mouse model of oculopharyngeal muscular dystrophy

Davies, J. E., Sarkar, S., & Rubinsztein, D. C. (2006) · Human Molecular Genetics

Genetic Neurodegenerative DiseasesMuscle Physiology and Disorders

Cited by 207