Southall, Noel

How Ions Affect the Structure of Water

Hribar, B., Southall, N. T., Vlachy, V., & Dill, K. A. (2002) · Journal of the American Chemical Society

Spectroscopy and Quantum Chemical StudiesAdvanced Physical and Chemical Molecular Interactions

Cited by 860

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Anastasiou, D., Yu, Y., Israelsen, W. J., Jiang, J.-K., Boxer, M. B., Hong, B. S., Tempel, W., Dimov, S., Shen, M., Jha, A., et al. (2012) · Nature Chemical Biology

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 816

Unexplored therapeutic opportunities in the human genome

Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., et al. (2018) · Nature Reviews Drug Discovery

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 378

Machine intelligence in healthcare—perspectives on trustworthiness, explainability, usability, and transparency

Cutillo, C. M., Sharma, K. R., Foschini, L., Kundu, S., Mackintosh, M., Mandl, K. D., MI in Healthcare Workshop Working Group, Beck, T., Collier, E., Colvis, C., et al. (2020) · npj Digital Medicine

Artificial Intelligence in Healthcare and EducationExplainable Artificial Intelligence (XAI)

Cited by 337

Pharos: collating protein information to shed light on the druggable genome

Nguyen, D.-T., Mathias, S., Bologa, C., Brunak, S., Fernandez, N., Gaulton, A., Hersey, A., Holmes, J., Jensen, L. J., Karlsson, A., et al. (2017) · Nucleic Acids Research

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 279

Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome

Rhyasen, G. W., Bolanos, L., Fang, J., Jerez, A., Wunderlich, M., Rigolino, C., Mathews, L., Ferrer, M., Southall, N., Guha, R., et al. (2013) · Cancer Cell

Acute Myeloid Leukemia ResearchCancer-related Molecular Pathways

Cited by 199

TCRD and pharos 2021: mining the human proteome for disease biology

Sheils, T. K., Mathias, S. L., Kelleher, K. J., Siramshetty, V. B., Nguyen, D.-T., Bologa, C. G., Jensen, L. J., Vidović, D., Koleti, A., Schürer, S. C., et al. (2021) · Nucleic Acids Research

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 160

Macrophage models of Gaucher disease for evaluating disease pathogenesis and candidate drugs

Aflaki, E., Stubblefield, B. K., Maniwang, E., Lopez, G., Moaven, N., Goldin, E., Marugan, J., Patnaik, S., Dutra, A., Southall, N., et al. (2014) · Science Translational Medicine

Lysosomal Storage Disorders ResearchGlycogen Storage Diseases and Myoclonus

Cited by 126

Identification of small-molecule agonists of human relaxin family receptor 1 (RXFP1) by using a homogenous cell-based cAMP assay

Chen, C. Z., Southall, N., Xiao, J., Marugan, J. J., Ferrer, M., Hu, X., Jones, R. E., Feng, S., Agoulnik, I. U., Zheng, W., et al. (2013) · SLAS Discovery

Pregnancy-related medical researchReceptor Mechanisms and Signaling

Cited by 31