Fallarino, Francesca

Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22

Zelante, T., Iannitti, R. G., Cunha, C., De Luca, A., Giovannini, G., Pieraccini, G., Zecchi, R., D’Angelo, C., Massi-Benedetti, C., Fallarino, F., et al. (2013) · Immunity

Gut microbiota and healthTryptophan and brain disorders

Cited by 2,614

Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond

Platten, M., Nollen, E. A. A., Röhrig, U. F., Fallarino, F., & Opitz, C. A. (2019) · Nature Reviews Drug Discovery

Tryptophan and brain disordersAmino Acid Enzymes and Metabolism

Cited by 1,586

T cell apoptosis by tryptophan catabolism

Fallarino, F., Grohmann, U., Vacca, C., Bianchi, R., Orabona, C., Spreca, A., Fioretti, M. C., & Puccetti, P. (2002) · Cell Death & Differentiation

Tryptophan and brain disordersT-cell and B-cell Immunology

Cited by 1,022

BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

Watanabe, N., Gavrieli, M., Sedy, J. R., Yang, J., Fallarino, F., Loftin, S. K., Hurchla, M. A., Zimmerman, N., Sim, J., Zang, X., et al. (2003) · Nature Immunology

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 883

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

Romani, L., Fallarino, F., De Luca, A., Montagnoli, C., D’Angelo, C., Zelante, T., Vacca, C., Bistoni, F., Fioretti, M. C., Grohmann, U., et al. (2008) · Nature

Neutrophil, Myeloperoxidase and Oxidative MechanismsTryptophan and brain disorders

Cited by 535

IL-22 defines a novel immune pathway of antifungal resistance

De Luca, A., Zelante, T., D'Angelo, C., Zagarella, S., Fallarino, F., Spreca, A., Iannitti, R. G., Bonifazi, P., Renauld, J.-C., Bistoni, F., et al. (2010) · Mucosal Immunology

Antifungal resistance and susceptibilityPsoriasis: Treatment and Pathogenesis

Cited by 265

Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration

Meliani, A., Boisgerault, F., Hardet, R., Marmier, S., Collaud, F., Ronzitti, G., Leborgne, C., Costa Verdera, H., Simon Sola, M., Charles, S., et al. (2018) · Nature Communications

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 265

TLR3 essentially promotes protective class I–restricted memory CD8+ T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients

Carvalho, A., De Luca, A., Bozza, S., Cunha, C., D'Angelo, C., Moretti, S., Perruccio, K., Iannitti, R. G., Fallarino, F., Pierini, A., et al. (2012) · Blood

Antifungal resistance and susceptibilityT-cell and B-cell Immunology

Cited by 131

Ligand Binding and Functional Selectivity of l-Tryptophan Metabolites at the Mouse Aryl Hydrocarbon Receptor (mAhR)

Nuti, R., Gargaro, M., Matino, D., Dolciami, D., Grohmann, U., Puccetti, P., Fallarino, F., & Macchiarulo, A. (2014) · Journal of Chemical Information and Modeling

Computational Drug Discovery MethodsToxic Organic Pollutants Impact

Cited by 45