Haider, Shozeb

Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands

Jin, S. C., Homsy, J., Zaidi, S., Lu, Q., Morton, S., DePalma, S. R., Zeng, X., Qi, H., Chang, W., Sierant, M. C., et al. (2017) · Nature Genetics

Congenital heart defects researchGenomics and Rare Diseases

Cited by 875

Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth

Sangodkar, J., Perl, A., Tohme, R., Kiselar, J., Kastrinsky, D. B., Zaware, N., Izadmehr, S., Mazhar, S., Wiredja, D. D., O’Connor, C. M., et al. (2017) · Journal of Clinical Investigation

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 196

Structure-phenotype correlations of human CYP21A2 mutations in congenital adrenal hyperplasia

Haider, S., Islam, B., D’Atri, V., Sgobba, M., Poojari, C., Sun, L., Yuen, T., Zaidi, M., & New, M. I. (2013) · Proceedings of the National Academy of Sciences

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 127

Differential affinity of FLIP and procaspase 8 for FADD’s DED binding surfaces regulates DISC assembly

Majkut, J., Sgobba, M., Holohan, C., Crawford, N., Logan, A. E., Kerr, E., Higgins, C. A., Redmond, K. L., Riley, J. S., Stasik, I., et al. (2014) · Nature Communications

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 81

Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors

O’Connor, C. M., Leonard, D., Wiredja, D., Avelar, R. A., Wang, Z., Schlatzer, D., Bryson, B., Tokala, E., Taylor, S. E., Upadhyay, A., et al. (2020) · Oncogene

Protein Tyrosine PhosphatasesMelanoma and MAPK Pathways

Cited by 48

Revealing druggable cryptic pockets in the Nsp1 of SARS-CoV-2 and other β-coronaviruses by simulations and crystallography

Borsatto, A., Akkad, O., Galdadas, I., Ma, S., Damfo, S., Haider, S., Kozielski, F., Estarellas, C., & Gervasio, F. L. (2022) · eLife

SARS-CoV-2 and COVID-19 ResearchComputational Drug Discovery Methods

Cited by 32

Functionally important residues from graph analysis of coevolved dynamic couplings

Xu, M., Dantu, S. C., Garnett, J. A., Bonomo, R. A., Pandini, A., & Haider, S. (2025) · eLife

Protein Structure and DynamicsEvolution and Genetic Dynamics

Cited by 3