Griffiths, John R.
University of Cambridge · Cancer Research UK
5 papers on CoChatORCID 0000-0001-7369-6836
Most cited papers
- Verified
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
Olive, K. P., Jacobetz, M. A., Davidson, C. J., Gopinathan, A., McIntyre, D., Honess, D., Madhu, B., Goldgraben, M. A., Caldwell, M. E., Allard, D., et al. (2009) · Science
Pancreatic and Hepatic Oncology ResearchHedgehog Signaling Pathway Studies
Cited by 3,170
- Verified
S-2-hydroxyglutarate regulates CD8(+) T-lymphocyte fate
Tyrakis, P. A., Palazon, A., Macias, D., Lee, K. L., Phan, A. T., Veliça, P., You, J., Chia, G. S., Sim, J., Doedens, A., et al. (2016) · Nature
T-cell and B-cell ImmunologyCancer, Hypoxia, and Metabolism
Cited by 433
- Verified
HIF-1-Independent Mechanisms Regulating Metabolic Adaptation in Hypoxic Cancer Cells
Lee, S.-H., Golinska, M., & Griffiths, J. R. (2021) · Cells
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 169
- Verified
Effects of HIF-1 and HIF2 on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts
Biswas, S., Troy, H., Leek, R., Chung, Y.-L., Li, J.-L., Raval, R. R., Turley, H., Gatter, K., Pezzella, F., Griffiths, J. R., et al. (2010) · Journal of Oncology
Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment
Cited by 89
- Verified
Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas
Golinska, M., Troy, H., Chung, Y.-L., McSheehy, P. M., Mayr, M., Yin, X., Ly, L., Williams, K. J., Airley, R. E., Harris, A. L., et al. (2011) · BMC Cancer
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 29
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