Hancock, John F.

Post‐translational processing of p21ras is two‐step and involves carboxyl‐methylation and carboxy‐terminal proteolysis.

Gutierrez, L., Magee, A. I., Marshall, C. J., & Hancock, J. F. (1989) · The EMBO Journal

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

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Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles

Kirkham, M., Fujita, A., Chadda, R., Nixon, S. J., Kurzchalia, T. V., Sharma, D. K., Pagano, R. E., Hancock, J. F., Mayor, S., & Parton, R. G. (2005) · The Journal of Cell Biology

Caveolin-1 and cellular processesCellular transport and secretion

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Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells

Howes, M. T., Kirkham, M., Riches, J., Cortese, K., Walser, P. J., Simpson, F., Hill, M. M., Jones, A., Lundmark, R., Lindsay, M. R., et al. (2010) · Journal of Cell Biology

Cellular transport and secretionCaveolin-1 and cellular processes

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Inhibition of RAS function through targeting an allosteric regulatory site

Spencer-Smith, R., Koide, A., Zhou, Y., Eguchi, R. R., Sha, F., Gajwani, P., Santana, D., Gupta, A., Jacobs, M., Herrero-Garcia, E., et al. (2017) · Nature Chemical Biology

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

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Discovery of High-Affinity Noncovalent Allosteric KRAS Inhibitors That Disrupt Effector Binding

McCarthy, M. J., Pagba, C. V., Prakash, P., Naji, A. K., van der Hoeven, D., Liang, H., Gupta, A. K., Zhou, Y., Cho, K.-J., Hancock, J. F., et al. (2019) · ACS Omega

Protein Kinase Regulation and GTPase SignalingComputational Drug Discovery Methods

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Lipid Profiles of RAS Nanoclusters Regulate RAS Function

Zhou, Y., & Hancock, J. F. (2021) · Biomolecules

Protein Kinase Regulation and GTPase SignalingLipid Membrane Structure and Behavior

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