Mäkelä, Tomi P.

FinnGen provides genetic insights from a well-phenotyped isolated population

Kurki, M. I., Karjalainen, J., Palta, P., Sipilä, T. P., Kristiansson, K., Donner, K. M., Reeve, M. P., Laivuori, H., Aavikko, M., Kaunisto, M. A., et al. (2023) · Nature

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 4,233

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Bellenguez, C., Küçükali, F., Jansen, I. E., Kleineidam, L., Moreno-Grau, S., Amin, N., Naj, A. C., Campos-Martin, R., Grenier-Boley, B., Andrade, V., et al. (2022) · Nature Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 2,498

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1

Lizcano, J. M., Göransson, O., Toth, R., Deak, M., Morrice, N. A., Boudeau, J., Hawley, S. A., Udd, L., Mäkelä, T. P., Hardie, D. G., et al. (2004) · The EMBO Journal

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 1,381

Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox‐1 homeobox transcription factor

Petrova, T. V., Mäkinen, T., Mäkelä, T. P., Saarela, J., Virtanen, I., Ferrell, R. E., Finegold, D. N., Kerjaschki, D., Ylä‐Herttuala, S., & Alitalo, K. (2002) · The EMBO Journal

Lymphatic System and DiseasesLymphatic Disorders and Treatments

Cited by 632

p21 Inhibits Thr161 Phosphorylation of Cdc2 to Enforce the G2 DNA Damage Checkpoint

Smits, V. A. J., Klompmaker, R., Vallenius, T., Rijksen, G., Mäkelä, T. P., & Medema, R. H. (2000) · Journal of Biological Chemistry

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 221

AMPK negatively regulates tensin-dependent integrin activity

Georgiadou, M., Lilja, J., Jacquemet, G., Guzmán, C., Rafaeva, M., Alibert, C., Yan, Y., Sahgal, P., Lerche, M., Manneville, J.-B., et al. (2017) · Journal of Cell Biology

Cell Adhesion Molecules ResearchCellular Mechanics and Interactions

Cited by 109

The cellular response to induction of the p21 c‐Ha‐ras oncoprotein includes stimulation of jun gene expression.

Sistonen, L., Hölttä, E., Mäkelä, T. P., Keski‐Oja, J., & Alitalo, K. (1989) · The EMBO Journal

Protein Kinase Regulation and GTPase SignalingPolyamine Metabolism and Applications

Cited by 109

Inactivation of AMPK leads to attenuation of antigen presentation and immune evasion in lung adenocarcinoma

Gao, Y., Päivinen, P., Tripathi, S., Domènech-Moreno, E., Wong, I. P. L., Vaahtomeri, K., Nagaraj, A. S., Talwelkar, S. S., Foretz, M., Verschuren, E. W., et al. (2022) · Clinical Cancer Research

Cancer Immunotherapy and BiomarkersMetabolism, Diabetes, and Cancer

Cited by 40