Aikata, Hiroshi

The evolutionary history of 2,658 cancers

Gerstung, M., Jolly, C., Leshchiner, I., Dentro, S. C., Gonzalez, S., Rosebrock, D., Mitchell, T. J., Rubanova, Y., Anur, P., Yu, K., et al. (2020) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 1,057

Patterns of somatic structural variation in human cancer genomes

Li, Y., Roberts, N. D., Wala, J. A., Shapira, O., Schumacher, S. E., Kumar, K., Khurana, E., Waszak, S., Korbel, J. O., Haber, J. E., et al. (2020) · Nature

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 867

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Cortés-Ciriano, I., Lee, J. J.-K., Xi, R., Jain, D., Jung, Y. L., Yang, L., Gordenin, D., Klimczak, L. J., Zhang, C.-Z., Pellman, D. S., et al. (2020) · Nature Genetics

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 712

Lenvatinib plus pembrolizumab versus lenvatinib plus placebo for advanced hepatocellular carcinoma (LEAP-002): a randomised, double-blind, phase 3 trial

Llovet, J. M., Kudo, M., Merle, P., Meyer, T., Qin, S., Ikeda, M., Xu, R., Edeline, J., Ryoo, B.-Y., Ren, Z., et al. (2023) · The Lancet Oncology

Hepatocellular Carcinoma Treatment and PrognosisColorectal Cancer Treatments and Studies

Cited by 469

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Rodriguez-Martin, B., Alvarez, E. G., Baez-Ortega, A., Zamora, J., Supek, F., Demeulemeester, J., Santamarina, M., Ju, Y. S., Temes, J., Garcia-Souto, D., et al. (2020) · Nature Genetics

Genomic variations and chromosomal abnormalitiesCancer Genomics and Diagnostics

Cited by 451

Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

Akdemir, K. C., Le, V. T., Chandran, S., Li, Y., Verhaak, R. G., Beroukhim, R., Campbell, P. J., Chin, L., Dixon, J. R., Futreal, P. A., et al. (2020) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 283

Telomere reduction in human liver tissues with age and chronic inflammation

Aikata, H., Takaishi, H., Kawakami, Y., Takahashi, S., Kitamoto, M., Nakanishi, T., Nakamura, Y., Shimamoto, F., Kajiyama, G., & Ide, T. (2000) · Experimental Cell Research

Telomeres, Telomerase, and SenescenceLiver physiology and pathology

Cited by 174

Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice

Furusho, H., Miyauchi, M., Hyogo, H., Inubushi, T., Ao, M., Ouhara, K., Hisatune, J., Kurihara, H., Sugai, M., Hayes, C. N., et al. (2013) · Journal of Gastroenterology

Liver Disease Diagnosis and TreatmentOral microbiology and periodontitis research

Cited by 157

Differences in serum microRNA profiles in hepatitis B and C virus infection

Akamatsu, S., Hayes, C. N., Tsuge, M., Miki, D., Akiyama, R., Abe, H., Ochi, H., Hiraga, N., Imamura, M., Takahashi, S., et al. (2015) · Journal of Infection

MicroRNA in disease regulationHepatitis B Virus Studies

Cited by 64

Proteo-Genomic Characterization of Virus-Associated Liver Cancers Reveals Potential Subtypes and Therapeutic Targets

Fujita, M., Chen, M.-J. M., Siwak, D. R., Sasagawa, S., Oosawa-Tatsuguchi, A., Arihiro, K., Ono, A., Miura, R., Maejima, K., Aikata, H., et al. (2022) · Nature Communications

Hepatocellular Carcinoma Treatment and PrognosisCancer Genomics and Diagnostics

Cited by 24