Ernst, Thomas

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

Ernst, T., Chase, A. J., Score, J., Hidalgo-Curtis, C. E., Bryant, C., Jones, A. V., Waghorn, K., Zoi, K., Ross, F. M., Reiter, A., et al. (2010) · Nature Genetics

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

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Inactivation of polycomb repressive complex 2 components in myeloproliferative and myelodysplastic/myeloproliferative neoplasms

Score, J., Hidalgo-Curtis, C., Jones, A. V., Winkelmann, N., Skinner, A., Ward, D., Zoi, K., Ernst, T., Stegelmann, F., Döhner, K., et al. (2012) · Blood

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

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Laying the foundation for genomically-based risk assessment in chronic myeloid leukemia

on behalf of the International CML Foundation Genomics Alliance, Branford, S., Kim, D. D. H., Apperley, J. F., Eide, C. A., Mustjoki, S., Ong, S. T., Nteliopoulos, G., Ernst, T., Chuah, C., et al. (2019) · Leukemia

Chronic Myeloid Leukemia TreatmentsChronic Lymphocytic Leukemia Research

Cited by 149

B-cell-specific diversion of glucose carbon utilization reveals a unique vulnerability in B cell malignancies

Xiao, G., Chan, L. N., Klemm, L., Braas, D., Chen, Z., Geng, H., Zhang, Q. C., Aghajanirefah, A., Cosgun, K. N., Sadras, T., et al. (2018) · Cell

Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress

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European LeukemiaNet laboratory recommendations for the diagnosis and management of chronic myeloid leukemia

Cross, N. C. P., Ernst, T., Branford, S., Cayuela, J.-M., Deininger, M., Fabarius, A., Kim, D. D. H., Machova Polakova, K., Radich, J. P., Hehlmann, R., et al. (2023) · Leukemia

Chronic Myeloid Leukemia TreatmentsChronic Lymphocytic Leukemia Research

Cited by 120

ASXL1 mutations predict inferior molecular response to nilotinib treatment in chronic myeloid leukemia

Schönfeld, L., Rinke, J., Hinze, A., Nagel, S. N., Schäfer, V., Schenk, T., Fabisch, C., Brümmendorf, T. H., Burchert, A., le Coutre, P., et al. (2022) · Leukemia

Chronic Myeloid Leukemia TreatmentsAcute Myeloid Leukemia Research

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The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AML

Kahl, M., Brioli, A., Bens, M., Perner, F., Kresinsky, A., Schnetzke, U., Hinze, A., Sbirkov, Y., Stengel, S., Simonetti, G., et al. (2019) · Leukemia

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

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Impact of BCR::ABL1 transcript type on RT-qPCR amplification performance and molecular response to therapy

Salmon, M., White, H. E., Zizkova, H., Gottschalk, A., Motlova, E., Cerveira, N., Colomer, D., Coriu, D., Franke, G. N., Gottardi, E., et al. (2022) · Leukemia

Chronic Myeloid Leukemia TreatmentsMolecular Biology Techniques and Applications

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Treatment Free Remission after Nilotinib Plus Peg-Interferon Alpha Induction and Peg-Interferon Alpha Maintenance Therapy for Newly Diagnosed Chronic Myeloid Leukemia Patients; The Tiger Trial

Hochhaus, A., Burchert, A., Saussele, S., Baerlocher, G. M., Mayer, J., Brümmendorf, T. H., La Rosée, P., Heim, D., Krause, S. W., le Coutre, P., et al. (2023) · Blood

Chronic Myeloid Leukemia TreatmentsChronic Lymphocytic Leukemia Research

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