Giacca, Mauro

Functional screening identifies miRNAs inducing cardiac regeneration

Eulalio, A., Mano, M., Ferro, M. D., Zentilin, L., Sinagra, G., Zacchigna, S., & Giacca, M. (2012) · Nature

Congenital heart defects researchCardiac Fibrosis and Remodeling

Cited by 1,029

Identification of HSP90 inhibitors as a novel class of senolytics

Fuhrmann-Stroissnigg, H., Ling, Y. Y., Zhao, J., McGowan, S. J., Zhu, Y., Brooks, R. W., Grassi, D., Gregg, S. Q., Stripay, J. L., Dorronsoro, A., et al. (2017) · Nature Communications

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 701

MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs

Gabisonia, K., Prosdocimo, G., Aquaro, G. D., Carlucci, L., Zentilin, L., Secco, I., Ali, H., Braga, L., Gorgodze, N., Bernini, F., et al. (2019) · Nature

Congenital heart defects researchCardiac Fibrosis and Remodeling

Cited by 478

Virus-mediated gene delivery for human gene therapy

Giacca, M., & Zacchigna, S. (2012) · Journal of Controlled Release

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 302

Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material

Lock, M., McGorray, S., Auricchio, A., Ayuso, E., Beecham, E. J., Blouin-Tavel, V., Bosch, F., Bose, M., Byrne, B. J., Caton, T., et al. (2010) · Human Gene Therapy

Virus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects

Cited by 131

The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication

Schwartz, R. A., Palacios, J. A., Cassell, G. D., Adam, S., Giacca, M., & Weitzman, M. D. (2007) · Journal of Virology

Virus-based gene therapy researchDNA Repair Mechanisms

Cited by 130

VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9

Montagna, C., Petris, G., Casini, A., Maule, G., Franceschini, G. M., Zanella, I., Conti, L., Arnoldi, F., Burrone, O. R., Zentilin, L., et al. (2018) · Molecular Therapy Nucleic Acids

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 117

Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material

Ayuso, E., Blouin, V., Lock, M., McGorray, S., Leon, X., Alvira, M. R., Auricchio, A., Bucher, S., Chtarto, A., Clark, K. R., et al. (2014) · Human Gene Therapy

Virus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects

Cited by 94

Intramyocardial VEGF-B 167 Gene Delivery Delays the Progression Towards Congestive Failure in Dogs With Pacing-Induced Dilated Cardiomyopathy

Pepe, M., Mamdani, M., Zentilin, L., Csiszar, A., Qanud, K., Zacchigna, S., Ungvari, Z., Puligadda, U., Moimas, S., Xu, X., et al. (2010) · Circulation Research

Cardiomyopathy and Myosin StudiesCardiac Fibrosis and Remodeling

Cited by 93

Processing of recombinant AAV genomes occurs in specific nuclear structures that overlap with foci of DNA-damage-response proteins

Cervelli, T., Palacios, J. A., Zentilin, L., Mano, M., Schwartz, R. A., Weitzman, M. D., & Giacca, M. (2008) · Journal of Cell Science

Virus-based gene therapy researchDNA Repair Mechanisms

Cited by 84

Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins

Lovric, J., Mano, M., Zentilin, L., Eulalio, A., Zacchigna, S., & Giacca, M. (2012) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 77

Roadmap for alleviating the manifestations of ageing in the cardiovascular system

Liberale, L., Tual-Chalot, S., Sedej, S., Ministrini, S., Georgiopoulos, G., Grunewald, M., Bäck, M., Bochaton-Piallat, M.-L., Boon, R. A., Ramos, G. C., et al. (2025) · Nature Reviews Cardiology

Cardiovascular Health and Disease PreventionTelomeres, Telomerase, and Senescence

Cited by 59

SREBP2 gene therapy targeting striatal astrocytes ameliorates Huntington’s disease phenotypes

Birolini, G., Verlengia, G., Talpo, F., Maniezzi, C., Zentilin, L., Giacca, M., Conforti, P., Cordiglieri, C., Caccia, C., Leoni, V., et al. (2021) · Brain

Genetic Neurodegenerative DiseasesLysosomal Storage Disorders Research

Cited by 48

Gene amplification for c-erbB-2, c-myc, epidermal growth factor receptor, int-2, and N-myc measured by quantitative PCR with a multiple competitor template

Sestini, R., Orlando, C., Zentilin, L., Lami, D., Gelmini, S., Pinzani, P., Giacca, M., & Pazzagli, M. (1995) · Clinical Chemistry

Molecular Biology Techniques and ApplicationsHER2/EGFR in Cancer Research

Cited by 44

Genome-wide RNAi screening identifies host restriction factors critical for in vivo AAV transduction

Mano, M., Ippodrino, R., Zentilin, L., Zacchigna, S., & Giacca, M. (2015) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 39

Repeated AAV-mediated gene transfer by serotype switching enables long-lasting therapeutic levels of hUgt1a1 enzyme in a mouse model of crigler–najjar syndrome type I

Bočkor, L., Bortolussi, G., Iaconcig, A., Chiaruttini, G., Tiribelli, C., Giacca, M., Benvenuti, F., Zentilin, L., & Muro, A. F. (2017) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 32