Valkov, Eugene

Retroviral intasome assembly and inhibition of DNA strand transfer

Hare, S., Gupta, S. S., Valkov, E., Engelman, A., & Cherepanov, P. (2010) · Nature

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 678

A Molecular Mechanism for Bacterial Susceptibility to Zinc

McDevitt, C. A., Ogunniyi, A. D., Valkov, E., Lawrence, M. C., Kobe, B., McEwan, A. G., & Paton, J. C. (2011) · PLoS Pathogens

Bacterial Genetics and BiotechnologyTrace Elements in Health

Cited by 484

A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75

Hare, S., Shun, M.-C., Gupta, S. S., Valkov, E., Engelman, A., & Cherepanov, P. (2009) · PLoS Pathogens

Virus-based gene therapy researchHIV Research and Treatment

Cited by 166

Functional and structural characterization of the integrase from the prototype foamy virus

Valkov, E., Gupta, S. S., Hare, S., Helander, A., Roversi, P., McClure, M., & Cherepanov, P. (2009) · Nucleic Acids Research

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 130

Targeting Protein–Protein Interactions and Fragment-Based Drug Discovery

Valkov, E., Sharpe, T., Marsh, M., Greive, S., & Hyvönen, M. (2011) · Topics in Current Chemistry

Computational Drug Discovery MethodsChemical Synthesis and Analysis

Cited by 107

Attenuating ribosome load improves protein output from mRNA by limiting translation-dependent mRNA decay

Bicknell, A. A., Reid, D. W., Licata, M. C., Jones, A. K., Cheng, Y. M., Li, M., Hsiao, C. J., Pepin, C. S., Metkar, M., Levdansky, Y., et al. (2024) · Cell Reports

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 68

Deadenylation kinetics of mixed poly(A) tails at single-nucleotide resolution

Lee, Y.-S., Levdansky, Y., Jung, Y., Kim, V. N., & Valkov, E. (2024) · Nature Structural & Molecular Biology

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 21

RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria

Behera, A. K., Kim, J. J., Kordale, S., Pekovic, F., Damodaran, A. P., Kumari, B., Vidak, S., Dickson, E., Xiao, M.-S., Duncan, G., et al. (2026) · Molecular Cell

RNA Research and SplicingNuclear Structure and Function

Cited by 6

Human pumilio proteins use fuzzy multivalent hydrophobic interactions to recruit the CCR4–NOT deadenylase complex to repress mRNAs

Dunshee, E. B., Saladin, B. A., Turner, D. J., Qiu, C., Dutcher, R. C., Williams, J. G., Corbo, J., Wolcott, O. R., Korte, A. J., Haugen, R. J., et al. (2026) · Journal of Biological Chemistry

RNA Research and SplicingProtein Structure and Dynamics

Cited by 1

Human Pumilio proteins use fuzzy multivalent hydrophobic interactions to recruit the CCR4–NOT deadenylase complex to repress mRNAs

Dunshee, E. B., Saladin, B. A., Turner, D. J., Qiu, C., Dutcher, R. C., Williams, J. G., Corbo, J., Wolcott, O. R., Korte, A. J., Haugen, R. J., et al. (2025) · Journal of Biological Chemistry

RNA Research and SplicingProtein Structure and Dynamics

Cited by 1