McCabe, Michael T.

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

McCabe, M. T., Ott, H. M., Ganji, G., Korenchuk, S., Thompson, C., Van Aller, G. S., Liu, Y., Graves, A. P., III, A. D. P., Diaz, E., et al. (2012) · Nature

Epigenetics and DNA MethylationCancer-related gene regulation

Cited by 1,786

Reductive carboxylation supports redox homeostasis during anchorage-independent growth

Jiang, L., Shestov, A. A., Swain, P., Yang, C., Parker, S. J., Wang, Q. A., Terada, L. S., Adams, N. D., McCabe, M. T., Pietrak, B., et al. (2016) · Nature

Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress

Cited by 582

Natural mutagenesis of human genomes by endogenous retrotransposons

Iskow, R. C., McCabe, M. T., Mills, R. E., Torene, S., Pittard, W. S., Neuwald, A. F., Van Meir, E. G., Vertino, P. M., & Devine, S. E. (2010) · Cell

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 551

New IDH1 mutant inhibitors for treatment of acute myeloid leukemia

Okoye-Okafor, U. C., Bartholdy, B., Cartier, J., Gao, E. N., Pietrak, B., Rendina, A. R., Rominger, C., Quinn, C., Smallwood, A., Wiggall, K. J., et al. (2015) · Nature Chemical Biology

Acute Myeloid Leukemia ResearchGlioma Diagnosis and Treatment

Cited by 180

Regulation of DNA Methyltransferase 1 by the pRb/E2F1 Pathway

McCabe, M. T., Davis, J. N., & Day, M. L. (2005) · Cancer Research

Epigenetics and DNA MethylationCancer-related gene regulation

Cited by 172

Abstract 2994: Discovery of selective, noncovalent small molecule inhibitors of DNMT1 as an alternative to traditional DNA hypomethylating agents

Pappalardi, M. B., Cockerill, M., Handler, J. L., Stowell, A., Keenan, K., Sherk, C. S., Minthorn, E. A., McHugh, C. F., Burt, C., Wong, K., et al. (2018) · Cancer Research

Epigenetics and DNA MethylationHistone Deacetylase Inhibitors Research

Cited by 9

A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation

Ge, A. Y., Arab, A., Dai, R., Navickas, A., Fish, L., Garcia, K., Asgharian, H., Goudreau, J., Lee, S., Keenan, K., et al. (2024) · Scientific Reports

Epigenetics and DNA MethylationAcute Myeloid Leukemia Research

Cited by 4