Ruchala, Piotr

Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models

Biczo, G., Vegh, E. T., Shalbueva, N., Mareninova, O. A., Elperin, J., Lotshaw, E., Gretler, S., Lugea, A., Malla, S. R., Dawson, D., et al. (2018) · Gastroenterology

Pancreatitis Pathology and TreatmentAutophagy in Disease and Therapy

Cited by 406

Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload

Preza, G. C., Ruchala, P., Pinon, R., Ramos, E., Qiao, B., Peralta, M. A., Sharma, S., Waring, A., Ganz, T., & Nemeth, E. (2011) · Journal of Clinical Investigation

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 234

Hepcidin-Induced Hypoferremia Is a Critical Host Defense Mechanism against the Siderophilic Bacterium Vibrio vulnificus

Arezes, J., Jung, G., Gabayan, V., Valore, E., Ruchala, P., Gulig, P. A., Ganz, T., Nemeth, E., & Bulut, Y. (2015) · Cell Host & Microbe

Iron Metabolism and DisordersVibrio bacteria research studies

Cited by 227

Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis

Ramos, E., Ruchala, P., Goodnough, J. B., Kautz, L., Preza, G. C., Nemeth, E., & Ganz, T. (2012) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 213

Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non-transferrin-bound iron

Stefanova, D., Raychev, A., Arezes, J., Ruchala, P., Gabayan, V., Skurnik, M., Dillon, B. J., Horwitz, M. A., Ganz, T., Bulut, Y., et al. (2017) · Blood

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 145

Interactions of α-, β-, and θ-Defensins with Influenza A Virus and Surfactant Protein D

Doss, M., White, M. R., Tecle, T., Gantz, D., Crouch, E. C., Jung, G., Ruchala, P., Waring, A. J., Lehrer, R. I., & Hartshorn, K. L. (2009) · The Journal of Immunology

Antimicrobial Peptides and ActivitiesInfluenza Virus Research Studies

Cited by 138

Hepcidin Protects against Lethal Escherichia coli Sepsis in Mice Inoculated with Isolates from Septic Patients

Stefanova, D., Raychev, A., Deville, J., Humphries, R., Campeau, S., Ruchala, P., Nemeth, E., Ganz, T., & Bulut, Y. (2018) · Infection and Immunity

Iron Metabolism and DisordersSepsis Diagnosis and Treatment

Cited by 68