Speicher, David W.

Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells

Roesch, A., Vultur, A., Bogeski, I., Wang, H., Zimmermann, K. M., Speicher, D., Körbel, C., Laschke, M. W., Gimotty, P. A., Philipp, S. E., et al. (2013) · Cancer Cell

Melanoma and MAPK PathwaysCancer Cells and Metastasis

Cited by 670

Cancer-associated fibroblasts neutralize the anti-tumor effect of CSF1 receptor blockade by inducing PMN-MDSC infiltration of tumors

Kumar, V., Donthireddy, L., Marvel, D., Condamine, T., Wang, F., Lavilla-Alonso, S., Hashimoto, A., Vonteddu, P., Behera, R., Goins, M. A., et al. (2017) · Cancer Cell

Immune cells in cancerAngiogenesis and VEGF in Cancer

Cited by 653

NAD+ metabolism governs the proinflammatory senescence-associated secretome

Nacarelli, T., Lau, L., Fukumoto, T., Zundell, J., Fatkhutdinov, N., Wu, S., Aird, K. M., Iwasaki, O., Kossenkov, A. V., Schultz, D., et al. (2019) · Nature Cell Biology

Sirtuins and Resveratrol in MedicineTelomeres, Telomerase, and Senescence

Cited by 402

RETRACTED ARTICLE: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance

Kaur, A., Webster, M. R., Marchbank, K., Behera, R., Ndoye, A., Kugel, C. H., Dang, V. M., Appleton, J., O’Connell, M. P., Cheng, P., et al. (2016) · Nature

Melanoma and MAPK PathwaysWnt/β-catenin signaling in development and cancer

Cited by 398

The proteome of the mouse photoreceptor sensory cilium complex

Liu, Q., Tan, G., Levenkova, N., Li, T., Pugh, E. N., Rux, J. J., Speicher, D. W., & Pierce, E. A. (2007) · Molecular & Cellular Proteomics

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 359

Molecular Determinants for Targeting Heterochromatin Protein 1-Mediated Gene Silencing: Direct Chromoshadow Domain–KAP-1 Corepressor Interaction Is Essential

Lechner, M. S., Begg, G. E., Speicher, D. W., & Rauscher, F. J. (2000) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 210

PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma

Sharma, G., Ojha, R., Noguera-Ortega, E., Rebecca, V. W., Attanasio, J., Liu, S., Piao, S., Lee, J. J., Nicastri, M. C., Harper, S. L., et al. (2020) · JCI Insight

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 80