Lee, Hyungjun

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.

Mertens, J., Paquola, A. C. M., Ku, M., Hatch, E., Böhnke, L., Ladjevardi, S., McGrath, S., Campbell, B., Lee, H., Herdy, J. R., et al. (2015) · Cell Stem Cell

Pluripotent Stem Cells ResearchGenetics, Aging, and Longevity in Model Organisms

Cited by 765

Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients

Mertens, J., Herdy, J. R., Traxler, L., Schafer, S. T., Schlachetzki, J. C. M., Böhnke, L., Reid, D. A., Lee, H., Zangwill, D., Fernandes, D. P., et al. (2021) · Cell Stem Cell

Pluripotent Stem Cells ResearchAlzheimer's disease research and treatments

Cited by 240

Mitochondrial aging defects emerge in directly reprogrammed human neurons due to their metabolic profile

Kim, Y., Zheng, X., Ansari, Z., Bunnell, M. C., Herdy, J. R., Traxler, L., Lee, H., Paquola, A. C. M., Blithikioti, C., Ku, M., et al. (2018) · Cell Reports

Mitochondrial Function and PathologyPluripotent Stem Cells Research

Cited by 117

Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons

Herdy, J., Schafer, S., Kim, Y., Ansari, Z., Zangwill, D., Ku, M., Paquola, A., Lee, H., Mertens, J., & Gage, F. H. (2019) · eLife

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 64