Lupiáñez, Darío G.

Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions

Lupiáñez, D. G., Kraft, K., Heinrich, V., Krawitz, P., Brancati, F., Klopocki, E., Horn, D., Kayserili, H., Opitz, J. M., Laxova, R., et al. (2015) · Cell

Genomics and Chromatin DynamicsGenomic variations and chromosomal abnormalities

Cited by 2,132

Breaking TADs: How Alterations of Chromatin Domains Result in Disease

Lupiáñez, D. G., Spielmann, M., & Mundlos, S. (2016) · Trends in Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 439

In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation

Anania, C., Acemel, R. D., Jedamzick, J., Bolondi, A., Cova, G., Brieske, N., Kühn, R., Wittler, L., Real, F. M., & Lupiáñez, D. G. (2021) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 77

The little skate genome and the evolutionary emergence of wing-like fins

Marlétaz, F., de la Calle-Mustienes, E., Acemel, R. D., Paliou, C., Naranjo, S., Martínez-García, P. M., Cases, I., Sleight, V. A., Hirschberger, C., Marcet-Houben, M., et al. (2023) · Nature

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 71

The mole genome reveals regulatory rearrangements associated with adaptive intersexuality

M. Real, F., Haas, S. A., Franchini, P., Xiong, P., Simakov, O., Kuhl, H., Schöpflin, R., Heller, D., Moeinzadeh, M.-H., Heinrich, V., et al. (2020) · Science

Genetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesSexual Differentiation and Disorders

Cited by 66