Farin, Henner F.

Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells

Farin, H. F., Van Es, J. H., & Clevers, H. (2012) · Gastroenterology

Wnt/β-catenin signaling in development and cancerDigestive system and related health

Cited by 655

Replacement of lost Lgr5-positive stem cells through plasticity of their enterocyte-lineage daughters

Tetteh, P. W., Basak, O., Farin, H. F., Wiebrands, K., Kretzschmar, K., Begthel, H., van den Born, M., Korving, J., de Sauvage, F., van Es, J. H., et al. (2016) · Cell stem cell

Digestive system and related healthWnt/β-catenin signaling in development and cancer

Cited by 575

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche

Farin, H. F., Jordens, I., Mosa, M. H., Basak, O., Korving, J., Tauriello, D. V. F., de Punder, K., Angers, S., Peters, P. J., Maurice, M. M., et al. (2016) · Nature

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 525

3D model for CAR‐mediated cytotoxicity using patient‐derived colorectal cancer organoids

Schnalzger, T. E., de Groot, M. H., Zhang, C., Mosa, M. H., Michels, B. E., Röder, J., Darvishi, T., Wels, W. S., & Farin, H. F. (2019) · The EMBO Journal

CAR-T cell therapy researchImmune Cell Function and Interaction

Cited by 354

Controlled gene expression in primary Lgr5 organoid cultures

Koo, B.-K., Stange, D. E., Sato, T., Karthaus, W., Farin, H. F., Huch, M., van Es, J. H., & Clevers, H. (2012) · Nature Methods

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 320

Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids

Michels, B. E., Mosa, M. H., Streibl, B. I., Zhan, T., Menche, C., Abou-El-Ardat, K., Darvishi, T., Członka, E., Wagner, S., Winter, J., et al. (2020) · Cell Stem Cell

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 222

Colorectal cancer organoid-stroma biobank allows subtype-specific assessment of individualized therapy responses

Farin, H. F., Mosa, M. H., Ndreshkjana, B., Grebbin, B. M., Ritter, B., Menche, C., Kennel, K. B., Ziegler, P. K., Szabó, L., Bollrath, J., et al. (2023) · Cancer Discovery

Cancer Cells and MetastasisColorectal Cancer Treatments and Studies

Cited by 120

Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung

Lüdtke, T. H., Rudat, C., Wojahn, I., Weiss, A.-C., Kleppa, M.-J., Kurz, J., Farin, H. F., Moon, A., Christoffels, V. M., & Kispert, A. (2016) · Developmental Cell

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 69

Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer

Plattner, C., Lamberti, G., Blattmann, P., Kirchmair, A., Rieder, D., Loncova, Z., Sturm, G., Scheidl, S., Ijsselsteijn, M., Fotakis, G., et al. (2023) · iScience

Advanced Proteomics Techniques and ApplicationsColorectal Cancer Treatments and Studies

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