Pocai, Alessandro

Glucagon-like peptide 1 (GLP-1)

Müller, T. D., Finan, B., Bloom, S. R., D'Alessio, D., Drucker, D. J., Flatt, P. R., Fritsche, A., Gribble, F., Grill, H. J., Habener, J. F., et al. (2019) · Molecular Metabolism

Diabetes Treatment and ManagementRegulation of Appetite and Obesity

Cited by 1,868

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

El-Osta, A., Brasacchio, D., Yao, D., Pocai, A., Jones, P. L., Roeder, R. G., Cooper, M. E., & Brownlee, M. (2008) · The Journal of Experimental Medicine

Nitric Oxide and Endothelin EffectsAdvanced Glycation End Products research

Cited by 1,115

Hypothalamic KATP channels control hepatic glucose production

Pocai, A., Lam, T. K. T., Gutierrez-Juarez, R., Obici, S., Schwartz, G. J., Bryan, J., Aguilar-Bryan, L., & Rossetti, L. (2005) · Nature

Pancreatic function and diabetesRegulation of Appetite and Obesity

Cited by 645

Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis

Lam, T. K. T., Pocai, A., Gutierrez-Juarez, R., Obici, S., Bryan, J., Aguilar-Bryan, L., Schwartz, G. J., & Rossetti, L. (2005) · Nature Medicine

Regulation of Appetite and ObesityPancreatic function and diabetes

Cited by 432

Glucagon-Like Peptide 1/Glucagon Receptor Dual Agonism Reverses Obesity in Mice

Pocai, A., Carrington, P. E., Adams, J. R., Wright, M., Eiermann, G., Zhu, L., Du, X., Petrov, A., Lassman, M. E., Jiang, G., et al. (2009) · Diabetes

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 409

A brain-liver circuit regulates glucose homeostasis

Pocai, A., Obici, S., Schwartz, G. J., & Rossetti, L. (2005) · Cell Metabolism

Pancreatic function and diabetesRegulation of Appetite and Obesity

Cited by 392

Regulation of Blood Glucose by Hypothalamic Pyruvate Metabolism

Lam, T. K. T., Gutierrez-Juarez, R., Pocai, A., & Rossetti, L. (2005) · Science

Pancreatic function and diabetesRegulation of Appetite and Obesity

Cited by 341

Critical role of STAT3 in leptin's metabolic actions

Buettner, C., Pocai, A., Muse, E. D., Etgen, A. M., Myers, M. G., & Rossetti, L. (2006) · Cell Metabolism

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 228

Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats

Pocai, A. (2006) · Journal of Clinical Investigation

Regulation of Appetite and ObesityPeroxisome Proliferator-Activated Receptors

Cited by 211

Action and therapeutic potential of oxyntomodulin

Pocai, A. (2014) · Molecular Metabolism

Diabetes Treatment and ManagementRegulation of Appetite and Obesity

Cited by 191

Central Leptin Acutely Reverses Diet-Induced Hepatic Insulin Resistance

Pocai, A., Morgan, K., Buettner, C., Gutierrez-Juarez, R., Obici, S., & Rossetti, L. (2005) · Diabetes

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 153

Direct effect of GLP-1 infusion on endogenous glucose production in humans

Seghieri, M., Rebelos, E., Gastaldelli, A., Astiarraga, B. D., Casolaro, A., Barsotti, E., Pocai, A., Nauck, M., Muscelli, E., & Ferrannini, E. (2013) · Diabetologia

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 143

Optimization of co-agonism at GLP-1 and glucagon receptors to safely maximize weight reduction in DIO-rodents

Day, J. W., Gelfanov, V., Smiley, D., Carrington, P. E., Eiermann, G., Chicchi, G., Erion, M. D., Gidda, J., Thornberry, N. A., Tschöp, M. H., et al. (2012) · Peptide Science

Diabetes Treatment and ManagementRegulation of Appetite and Obesity

Cited by 133