Urh, Marjeta

Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity

Imaide, S., Riching, K. M., Makukhin, N., Vetma, V., Whitworth, C., Hughes, S. J., Trainor, N., Mahan, S. D., Murphy, N., Cowan, A. D., et al. (2021) · Nature Chemical Biology

Protein Degradation and InhibitorsChemical Synthesis and Analysis

Cited by 251

Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs

Bai, N., Riching, K. M., Makaju, A., Wu, H., Acker, T. M., Ou, S.-C., Zhang, Y., Shen, X., Bulloch, D. N., Rui, H., et al. (2022) · Journal of Biological Chemistry

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 77

Mass Spectrometry Compatible Surfactant for Optimized In-Gel Protein Digestion

Saveliev, S. V., Woodroofe, C. C., Sabat, G., Adams, C. M., Klaubert, D., Wood, K., & Urh, M. (2013) · Analytical Chemistry

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 62

Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines

Nishiguchi, G., Mascibroda, L. G., Young, S. M., Caine, E. A., Abdelhamed, S., Kooijman, J. J., Miller, D. J., Das, S., McGowan, K., Mayasundari, A., et al. (2024) · Nature Communications

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 57