Cavadini, Simone

Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide

Fischer, E. S., Böhm, K., Lydeard, J. R., Yang, H., Stadler, M. B., Cavadini, S., Nagel, J., Serluca, F., Acker, V., Lingaraju, G. M., et al. (2014) · Nature

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 1,141

The Molecular Basis of CRL4DDB2/CSA Ubiquitin Ligase Architecture, Targeting, and Activation

Fischer, E. S., Scrima, A., Böhm, K., Matsumoto, S., Lingaraju, G. M., Faty, M., Yasuda, T., Cavadini, S., Wakasugi, M., Hanaoka, F., et al. (2011) · Cell

Ubiquitin and proteasome pathwaysDNA Repair Mechanisms

Cited by 460

Structural mechanism of cGAS inhibition by the nucleosome

Pathare, G. R., Decout, A., Glück, S., Cavadini, S., Makasheva, K., Hovius, R., Kempf, G., Weiss, J., Kozicka, Z., Guey, B., et al. (2020) · Nature

interferon and immune responsesDNA and Nucleic Acid Chemistry

Cited by 273

Cullin–RING ubiquitin E3 ligase regulation by the COP9 signalosome

Cavadini, S., Fischer, E. S., Bunker, R. D., Potenza, A., Lingaraju, G. M., Goldie, K. N., Mohamed, W. I., Faty, M., Petzold, G., Beckwith, R. E. J., et al. (2016) · Nature

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 213

Structural basis of BRCC36 function in DNA repair and immune regulation

Rabl, J., Bunker, R. D., Schenk, A. D., Cavadini, S., Gill, M. E., Abdulrahman, W., Andrés-Pons, A., Luijsterburg, M. S., Ibrahim, A. F. M., Branigan, E., et al. (2019) · Molecular Cell

Ubiquitin and proteasome pathwaysDNA Repair Mechanisms

Cited by 84

UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability

Tsai, J. M., Aguirre, J. D., Li, Y.-D., Brown, J., Focht, V., Kater, L., Kempf, G., Sandoval, B., Schmitt, S., Rutter, J. C., et al. (2023) · Molecular Cell

Estrogen and related hormone effectsUbiquitin and proteasome pathways

Cited by 68

The genetic architecture of protein interaction affinity and specificity

Bendel, A. M., Faure, A. J., Klein, D., Shimada, K., Lyautey, R., Schiffelholz, N., Kempf, G., Cavadini, S., Lehner, B., & Diss, G. (2024) · Nature Communications

Protein Structure and DynamicsEvolution and Genetic Dynamics

Cited by 22

The genetic architecture of protein interaction affinity and specificity

Bendel, A. M., Faure, A. J., Klein, D., Shimada, K., Kempf, G., Cavadini, S., Lehner, B., & Diss, G. (2023) · Nature Communications

Protein Structure and DynamicsEvolution and Genetic Dynamics

Cited by 22