Michel, Julien

Targeting the von Hippel-Lindau E3 ubiquitin ligase using small molecules to disrupt the VHL/HIF-1α interaction

Buckley, D. L., Van Molle, I., Gareiss, P. C., Tae, H. S., Michel, J., Noblin, D. J., Jorgensen, W. L., Ciulli, A., & Crews, C. M. (2012) · Journal of the American Chemical Society

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 569

Assessment of Binding Affinity via Alchemical Free-Energy Calculations

Kuhn, M., Firth-Clark, S., Tosco, P., Mey, A. S. J. S., Mackey, M., & Michel, J. (2020) · Journal of Chemical Information and Modeling

Computational Drug Discovery MethodsAdvanced Chemical Physics Studies

Cited by 222

Biomolecular simulations: from dynamics and mechanisms to computational assays of biological activity

Huggins, D. J., Biggin, P. C., Dämgen, M. A., Essex, J. W., Harris, S. A., Henchman, R. H., Khalid, S., Kuzmanic, A., Laughton, C. A., Michel, J., et al. (2019) · WIREs Computational Molecular Science

Protein Structure and DynamicsAdvanced Physical and Chemical Molecular Interactions

Cited by 169

Dynamic design: manipulation of millisecond timescale motions on the energy landscape of Cyclophilin A

Juárez-Jiménez, J., Gupta, A. A., Karunanithy, G., Mey, A. S. J. S., Georgiou, C., Ioannidis, H., De Simone, A., Barlow, P. N., Hulme, A. N., Walkinshaw, M. D., et al. (2018) · Chemical Science

Protein Structure and DynamicsSignaling Pathways in Disease

Cited by 29

Assessment of the Topology and Oligomerisation States of Coiled Coils Using Metadynamics with Conformational Restraints

Notari, E., Wood, C. W., & Michel, J. (2025) · Journal of Chemical Theory and Computation

Protein Structure and DynamicsAdvanced Physical and Chemical Molecular Interactions

Cited by 4