Wijnholds, Jan

A family of drug transporters: the multidrug resistance-associated proteins

Borst, P., Evers, R., Kool, M., & Wijnholds, J. (2000) · JNCI Journal of the National Cancer Institute

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 1,751

TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals

Stöhr, H., Heisig, J. B., Benz, P. M., Schöberl, S., Milenkovic, V. M., Strauss, O., Aartsen, W. M., Wijnholds, J., Weber, B. H. F., & Schulz, H. L. (2009) · The Journal of Neuroscience

Ion channel regulation and functionNeuroscience and Neuropharmacology Research

Cited by 216

The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes

Minich, T., Riemer, J., Schulz, J. B., Wielinga, P., Wijnholds, J., & Dringen, R. (2006) · Journal of Neurochemistry

Drug Transport and Resistance MechanismsGlutathione Transferases and Polymorphisms

Cited by 185

Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Müller glia cells

van Rossum, A. G. S. H., Aartsen, W. M., Meuleman, J., Klooster, J., Malysheva, A., Versteeg, I., Arsanto, J.-P., Le Bivic, A., & Wijnholds, J. (2006) · Human Molecular Genetics

Retinal Development and DisordersConnexins and lens biology

Cited by 104

Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5

Quinn, P. M., Buck, T. M., Mulder, A. A., Ohonin, C., Alves, C. H., Vos, R. M., Bialecka, M., van Herwaarden, T., van Dijk, E. H. C., Talib, M., et al. (2019) · Stem Cell Reports

Retinal Development and DisordersVirus-based gene therapy research

Cited by 97

Recombinant Adeno-Associated Viral Vectors (rAAV)-Vector Elements in Ocular Gene Therapy Clinical Trials and Transgene Expression and Bioactivity Assays

Buck, T., & Wijnholds, J. (2020) · International Journal of Molecular Sciences

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 92

Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models

Pellissier, L. P., Quinn, P. M., Alves, C. H., Vos, R. M., Klooster, J., Flannery, J. G., Heimel, J. A., & Wijnholds, J. (2015) · Human Molecular Genetics

Retinal Development and DisordersVirus-based gene therapy research

Cited by 86

Specific tools for targeting and expression in Müller glial cells

Pellissier, L. P., Hoek, R. M., Vos, R. M., Aartsen, W. M., Klimczak, R. R., Hoyng, S. A., Flannery, J. G., & Wijnholds, J. (2014) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 58

GFAP-Driven GFP Expression in Activated Mouse Müller Glial Cells Aligning Retinal Blood Vessels Following Intravitreal Injection of AAV2/6 Vectors

Aartsen, W. M., van Cleef, K. W. R., Pellissier, L. P., Hoek, R. M., Vos, R. M., Blits, B., Ehlert, E. M. E., Balaggan, K. S., Ali, R. R., Verhaagen, J., et al. (2010) · PLoS ONE

Retinal Development and DisordersVirus-based gene therapy research

Cited by 41