Whitaker, Martin J.

Applications of supercritical CO2 in the fabrication of polymer systems for drug delivery and tissue engineering

Davies, O. R., Lewis, A. L., Whitaker, M. J., Tai, H., Shakesheff, K. M., & Howdle, S. M. (2008) · Advanced Drug Delivery Reviews

Phase Equilibria and ThermodynamicsPolymer Foaming and Composites

Cited by 299

A phase 2 study of Chronocort, a modified-release formulation of hydrocortisone, in the treatment of adults with classic congenital adrenal hyperplasia

Mallappa, A., Sinaii, N., Kumar, P., Whitaker, M. J., Daley, L.-A., Digweed, D., Eckland, D. J. A., Van Ryzin, C., Nieman, L. K., Arlt, W., et al. (2015) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 167

Salivary Cortisone Reflects Cortisol Exposure Under Physiological Conditions and After Hydrocortisone

Debono, M., Harrison, R. F., Whitaker, M. J., Eckland, D., Arlt, W., Keevil, B. G., & Ross, R. J. (2016) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 128

An oral multiparticulate, modified‐release, hydrocortisone replacement therapy that provides physiological cortisol exposure

Whitaker, M. J., Debono, M., Huatan, H., Merke, D. P., Arlt, W., & Ross, R. J. (2014) · Clinical Endocrinology

Adrenal Hormones and DisordersAdvanced Drug Delivery Systems

Cited by 121

Poor compliance and increased mortality, depression and healthcare costs in patients with congenital adrenal hyperplasia

Jenkins-Jones, S., Parviainen, L., Porter, J., Withe, M., Whitaker, M. J., Holden, S. E., Morgan, C. L., Currie, C. J., & Ross, R. J. M. (2018) · European Journal of Endocrinology

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 85

Modified release and conventional glucocorticoids and diurnal androgen excretion in congenital adrenal hyperplasia

Jones, C. M., Mallappa, A., Reisch, N., Nikolaou, N., Krone, N., Hughes, B. A., O’Neil, D. M., Whitaker, M. J., Tomlinson, J. W., Storbeck, K.-H., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 74

Home waking salivary cortisone to screen for adrenal insufficiency

Debono, M., Elder, C. J., Lewis, J., Fearnside, J., Caunt, S., Dixon, S., Jacques, R. M., Newell-Price, J., Whitaker, M. J., Keevil, B., et al. (2023) · NEJM Evidence

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 66

Absorption and tolerability of taste-masked hydrocortisone granules in neonates, infants and children under 6 years of age with adrenal insufficiency

Neumann, U., Whitaker, M. J., Wiegand, S., Krude, H., Porter, J., Davies, M., Digweed, D., Voet, B., Ross, R. J., & Blankenstein, O. (2018) · Clinical Endocrinology

Adrenal Hormones and DisordersPharmaceutical studies and practices

Cited by 64

Quality of compounded hydrocortisone capsules used in the treatment of children

Neumann, U., Burau, D., Spielmann, S., Whitaker, M. J., Ross, R. J., Kloft, C., & Blankenstein, O. (2017) · European Journal of Endocrinology

Adrenal Hormones and DisordersPharmaceutical studies and practices

Cited by 56

Development and Testing in Healthy Adults of Oral Hydrocortisone Granules With Taste Masking for the Treatment of Neonates and Infants With Adrenal Insufficiency

Whitaker, M. J., Spielmann, S., Digweed, D., Huatan, H., Eckland, D., Johnson, T. N., Tucker, G., Krude, H., Blankenstein, O., & Ross, R. J. (2015) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersPharmaceutical studies and practices

Cited by 48

A prospective study of children aged 0–8 years with cah and adrenal insufficiency treated with hydrocortisone granules

Neumann, U., Braune, K., Whitaker, M. J., Wiegand, S., Krude, H., Porter, J., Digweed, D., Voet, B., Ross, R. J. M., & Blankenstein, O. (2021) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 38

A Biopredictive In Vitro Approach for Assessing Compatibility of a Novel Pediatric Hydrocortisone Drug Product within Common Pediatric Dosing Vehicles

Wollmer, E., Karkossa, F., Freerks, L., Hetberg, A.-E., Neal, G., Porter, J., Whitaker, M. J., Margetson, D., & Klein, S. (2020) · Pharmaceutical Research

Pharmaceutical studies and practicesDrug Solubulity and Delivery Systems

Cited by 30

Salivary cortisone to estimate cortisol exposure and sampling frequency required based on serum cortisol measurements

Harrison, R. F., Debono, M., Whitaker, M. J., Keevil, B. G., Newell-Price, J., & Ross, R. J. (2019) · The Journal of Clinical Endocrinology & Metabolism

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 27

Predicting Cortisol Exposure from Paediatric Hydrocortisone Formulation Using a Semi-Mechanistic Pharmacokinetic Model Established in Healthy Adults

Melin, J., Parra-Guillen, Z. P., Hartung, N., Huisinga, W., Ross, R. J., Whitaker, M. J., & Kloft, C. (2018) · Clinical Pharmacokinetics

Adrenal Hormones and DisordersPharmaceutical studies and practices

Cited by 17

Insights in the maturational processes influencing hydrocortisone pharmacokinetics in congenital adrenal hyperplasia patients using a middle-out approach

Michelet, R., Bindellini, D., Melin, J., Neumann, U., Blankenstein, O., Huisinga, W., Johnson, T. N., Whitaker, M. J., Ross, R., & Kloft, C. (2023) · Frontiers in Pharmacology

Adrenal Hormones and DisordersPharmaceutical studies and practices

Cited by 5

A quantitative modeling framework to understand the physiology of the hypothalamic-pituitary-adrenal axis and interaction with cortisol replacement therapy

Bindellini, D., Michelet, R., Aulin, L. B. S., Melin, J., Neumann, U., Blankenstein, O., Huisinga, W., Whitaker, M. J., Ross, R., & Kloft, C. (2024) · Journal of Pharmacokinetics and Pharmacodynamics

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 4